Product Name
ATPase, Ca++ Transporting, Type 2C, Member 2 (ATP2C2), Recombinant Protein
Full Product Name
Recombinant ATPase, Ca++ Transporting, Type 2C, Member 2 (ATP2C2)
Product Synonym Names
SPCA2; Secretory Pathway Calcium ATPase 2; Secretory pathway Ca(2+)-ATPase 2; Calcium-transporting ATPase type 2C member 2
Product Gene Name
ATP2C2 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
Met1~Tyr106
3D Structure
ModBase 3D Structure for O75185
Host
Host: E Coli
Source: Prokaryotic Expression
Purity/Purification
> 90%
Form/Format
Freeze-Dried Powder; PBS, pH7.4, Containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Subcellular Location
Membrane
Reconstitution
Reconstitute in PBS or others.
Preparation and Storage
Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customera??s specifications, please inquire.
Other Notes
Small volumes of ATP2C2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for ATP2C2 recombinant protein
Signal Transduction
Applications Tested/Suitable for ATP2C2 recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
NCBI/Uniprot data below describe general gene information for ATP2C2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_055676
[Other Products]
NCBI GenBank Nucleotide #
NM_014861.3
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UniProt Primary Accession #
O75185
[Other Products]
UniProt Related Accession #
O75185[Other Products]
Molecular Weight
Predicted MW: 15.8kDa
Accurate MW: 19kDa
NCBI Official Full Name
calcium-transporting ATPase type 2C member 2 isoform 2
NCBI Official Synonym Full Names
ATPase secretory pathway Ca2+ transporting 2
NCBI Official Symbol
ATP2C2??[Similar Products]
NCBI Official Synonym Symbols
SPCA2
??[Similar Products]
NCBI Protein Information
calcium-transporting ATPase type 2C member 2
UniProt Protein Name
Calcium-transporting ATPase type 2C member 2
UniProt Synonym Protein Names
Secretory pathway Ca(2+)-ATPase 2
Protein Family
Calcium-transporting ATPase
UniProt Gene Name
ATP2C2??[Similar Products]
UniProt Synonym Gene Names
KIAA0703; SPCA2; ATPase 2C2??[Similar Products]
UniProt Entry Name
AT2C2_HUMAN
UniProt Comments for ATP2C2
ATP2C2: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.6.3.8; Membrane protein, integral; Hydrolase; Transporter; Transporter, ion channel; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 16q24.1
Cellular Component: Golgi membrane; integral to membrane
Molecular Function: protein binding; calcium-transporting ATPase activity; metal ion binding; ATP binding
Biological Process: metabolic process; transmembrane transport
Research Articles on ATP2C2
1. In total, four independent SNPs within DYX1C1 and ATP2C2 were found to be associated with MMR stronger than expected from multiple testing. To explore potential pathomechanisms, we annotated these variants with functional data including tissue-specific expression analysis and eQTLs.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
