Product Name
ATP2C2, Blocking Peptide
Full Product Name
ATP2C2 Peptide
Product Synonym Names
SPCA2; KIAA0703; SPCA2; Calcium-transporting ATPase type 2C member 2; ATPase 2C2; ATPase, Ca++ transporting, type 2C, member 2
Product Gene Name
ATP2C2 blocking peptide
[Similar Products]
ATP2C2 peptide (MBS153283) is used for blocking the activity of ATP2C2 antibody (MBS150680)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O75185
Concentration
200 ug/mL (lot specific)
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location
19 amino acids near the amino terminus of human ATP2C2.
Preparation and Storage
Store ATP2C2 peptide at -20 degree C, stable for one year.
Other Notes
Small volumes of ATP2C2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for ATP2C2 blocking peptide
Blocking (BL)
Application Notes for ATP2C2 blocking peptide
ATP2C2 peptide is used for blocking the activity of ATP2C2 antibody.
Western Blot (WB) of ATP2C2 blocking peptide
Western blot analysis of ATP2C2 in 3T3 cell lysate with ATP2C2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
NCBI/Uniprot data below describe general gene information for ATP2C2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_055676
[Other Products]
NCBI GenBank Nucleotide #
NM_014861.2
[Other Products]
UniProt Primary Accession #
O75185
[Other Products]
UniProt Secondary Accession #
Q5HYC3; Q5S053; Q68CQ2; B4DU76; E7ES94[Other Products]
UniProt Related Accession #
O75185[Other Products]
Molecular Weight
106,235 Da
NCBI Official Full Name
calcium-transporting ATPase type 2C member 2 isoform 2
NCBI Official Synonym Full Names
ATPase, Ca++ transporting, type 2C, member 2
NCBI Official Symbol
ATP2C2??[Similar Products]
NCBI Official Synonym Symbols
SPCA2
??[Similar Products]
NCBI Protein Information
calcium-transporting ATPase type 2C member 2; ATPase 2C2; secretory pathway Ca(2+)-ATPase 2; secretory pathway calcium ATPase 2
UniProt Protein Name
Calcium-transporting ATPase type 2C member 2
UniProt Synonym Protein Names
Secretory pathway Ca(2+)-ATPase 2
Protein Family
Calcium-transporting ATPase
UniProt Gene Name
ATP2C2??[Similar Products]
UniProt Synonym Gene Names
KIAA0703; SPCA2; ATPase 2C2??[Similar Products]
UniProt Entry Name
AT2C2_HUMAN
UniProt Comments for ATP2C2
ATP2C2: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transporter, ion channel; EC 3.6.3.8; Hydrolase; Transporter; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 16q24.1
Cellular Component: Golgi membrane; integral to membrane
Molecular Function: protein binding; calcium-transporting ATPase activity; metal ion binding; ATP binding
Biological Process: metabolic process; transmembrane transport
Research Articles on ATP2C2
1. Findings reveal a signaling pathway in which the Orai1-SPCA2 complex elicits constitutive store-independent Ca(2+) signaling that promotes tumorigenesis.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
