Product Name
Matrin-3 (Matr3), Recombinant Protein
Full Product Name
Recombinant Rat Matrin-3 (Matr3) , partial
Product Gene Name
Matr3 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
471-845; C-terminal protein
Sequence
SQKYKRIKKP EGKPDEKFDQ KQELGRVIHL SNLPHSGYSD SAVLKLAEPY GKIKNYILMR MKSQAFIEME TREDAMAMVD HCLKKALWFQ GRCVKVDLSE KYKKLVLRIP NRGIDLLKKD KSRKRSYSPD GKESPSDKKS KTDGAQKTEN PAEGKEQEEK SGEDGEKDTK DDQTEQEPSM LLESEDELLV DEEEAAALIE SGSSVGDETD LANLGDVSSD GKKEPSDKAV KKDASATSKK KLKKVDKIEE LDQENEAALE NGIKNEENTE PGAESAENAD DPNKDASDNS DGQNDENKED YTIPDEYRIG PYQPNVPGGI DYVIPKTGFY CKLCSLFYTN EEVAKNTHCS SLPHYQKLKK FLNKLAEERR QKKES
3D Structure
ModBase 3D Structure for P43244
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Matr3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Matr3 recombinant protein
This protein is localized in the nuclear matrix. It may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. Two transcript variants encoding the same protein have been identified for this gene.
NCBI/Uniprot data below describe general gene information for Matr3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_062022.2
[Other Products]
NCBI GenBank Nucleotide #
NM_019149.3
[Other Products]
UniProt Primary Accession #
P43244
[Other Products]
UniProt Secondary Accession #
O35833; Q5DVW1[Other Products]
UniProt Related Accession #
P43244[Other Products]
Molecular Weight
94,447 Da
NCBI Official Full Name
matrin-3
NCBI Official Synonym Full Names
matrin 3
NCBI Official Symbol
Matr3??[Similar Products]
NCBI Official Synonym Symbols
P130/MAT3
??[Similar Products]
NCBI Protein Information
matrin-3
UniProt Protein Name
Matrin-3
UniProt Synonym Protein Names
Nuclear scaffold protein p130/MAT3
UniProt Gene Name
Matr3??[Similar Products]
NCBI Summary for Matr3
an internal nuclear matrix protein [RGD, Feb 2006]
UniProt Comments for Matr3
May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway. May bind to specific miRNA hairpins ().
Research Articles on Matr3
1. P130 has the potential to play a variety of roles in
biological events not only in the nuclear scaffold but also in various subcellular compartments.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
