Product Name
MATR3, Blocking Peptide
Full Product Name
MATR3 Antibody (N-term) Blocking Peptide
Product Synonym Names
Matrin-3; MATR3; KIAA0723
Product Gene Name
MATR3 blocking peptide
[Similar Products]
Product Synonym Gene Name
KIAA0723[Similar Products]
Antibody/Peptide Pairs
MATR3 peptide (MBS9220563) is used for blocking the activity of MATR3 antibody (MBS9210255)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P43243
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Nucleus matrix.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of MATR3 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
MATR3 blocking peptide
May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs.
NCBI/Uniprot data below describe general gene information for MATR3. It may not necessarily be applicable to this product.
NCBI Accession #
P43243.2
[Other Products]
UniProt Primary Accession #
P43243
[Other Products]
UniProt Secondary Accession #
Q9UHW0; Q9UQ27; B7ZAV5; D3DQC3[Other Products]
UniProt Related Accession #
P43243[Other Products]
Molecular Weight
62,576 Da
NCBI Official Full Name
Matrin-3
NCBI Official Synonym Full Names
matrin 3
NCBI Official Symbol
MATR3??[Similar Products]
NCBI Official Synonym Symbols
MPD2; ALS21; VCPDM
??[Similar Products]
NCBI Protein Information
matrin-3
UniProt Protein Name
Matrin-3
UniProt Gene Name
MATR3??[Similar Products]
UniProt Synonym Gene Names
KIAA0723??[Similar Products]
UniProt Entry Name
MATR3_HUMAN
NCBI Summary for MATR3
This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X. [provided by RefSeq, Aug 2013]
UniProt Comments for MATR3
matrin 3: an acidic protein that is a component of the nuclear matrix. May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network.
Protein type: RNA-binding; RNA processing
Chromosomal Location of Human Ortholog: 5q31.2
Cellular Component: membrane; nuclear inner membrane; nucleoplasm
Molecular Function: protein binding; structural molecule activity
Disease: Amyotrophic Lateral Sclerosis 21
Research Articles on MATR3
1. Our findings indicate that mutations in Matrin 3 that are associated with ALS and myopathy do not dramatically alter the normal localization of the protein or readily induce inclusion formation.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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