Product Name
Rab 3 GAP p150, Polyclonal Antibody
Full Product Name
Rab 3 GAP p150 Polyclonal Antibody
Product Gene Name
anti-Rab 3 GAP p150 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9H2M9
Other Notes
Small volumes of anti-Rab 3 GAP p150 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Rab 3 GAP p150. It may not necessarily be applicable to this product.
NCBI Accession #
NP_036546.2
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NCBI GenBank Nucleotide #
NM_012414.3
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UniProt Primary Accession #
Q9H2M9
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UniProt Secondary Accession #
O75872; Q9HAB0; Q9UFJ7; Q9UQ15; A6H8V0[Other Products]
UniProt Related Accession #
Q9H2M9[Other Products]
Molecular Weight
23,361 Da
NCBI Official Full Name
rab3 GTPase-activating protein non-catalytic subunit
NCBI Official Synonym Full Names
RAB3 GTPase activating non-catalytic protein subunit 2
NCBI Official Symbol
RAB3GAP2??[Similar Products]
NCBI Official Synonym Symbols
p150; SPG69; WARBM2; RAB3GAP150; RAB3-GAP150
??[Similar Products]
NCBI Protein Information
rab3 GTPase-activating protein non-catalytic subunit
UniProt Protein Name
Rab3 GTPase-activating protein non-catalytic subunit
UniProt Synonym Protein Names
RGAP-iso; Rab3 GTPase-activating protein 150 kDa subunit; Rab3-GAP p150; Rab3-GAP150; Rab3-GAP regulatory subunit
UniProt Gene Name
RAB3GAP2??[Similar Products]
UniProt Synonym Gene Names
KIAA0839; Rab3-GAP150??[Similar Products]
NCBI Summary for Rab 3 GAP p150
The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.[provided by RefSeq, Oct 2009]
UniProt Comments for Rab 3 GAP p150
Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
Research Articles on Rab 3 GAP p150
1. show that FOXC1 regulates the expression of RAB3GAP1, RAB3GAP2 and SNAP25
Precautions
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Disclaimer
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