Product Name
GDAP1L1, Blocking Peptide
Full Product Name
GDAP1L1 Peptide - middle region
Product Gene Name
GDAP1L1 blocking peptide
[Similar Products]
Product Synonym Gene Name
dJ881L22.1; dJ995J12.1.1[Similar Products]
GDAP1L1 peptide (MBS3245510) is used for blocking the activity of GDAP1L1 antibody (MBS3220708)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
Synthetic peptide located within the following region: ELWLCGCAFT LADVLLGATL HRLKFLGLSK KYWEDGSRPN LQSFFERVQR
3D Structure
ModBase 3D Structure for Q96MZ0
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of GDAP1L1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
GDAP1L1 blocking peptide
The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene.
Product Categories/Family for GDAP1L1 blocking peptide
Peptide
Applications Tested/Suitable for GDAP1L1 blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for GDAP1L1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001243666.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001256737.1
[Other Products]
UniProt Primary Accession #
Q96MZ0
[Other Products]
UniProt Related Accession #
Q96MZ0[Other Products]
NCBI Official Synonym Full Names
ganglioside induced differentiation associated protein 1 like 1
NCBI Official Symbol
GDAP1L1??[Similar Products]
NCBI Official Synonym Symbols
dJ881L22.1; dJ995J12.1.1
??[Similar Products]
NCBI Protein Information
ganglioside-induced differentiation-associated protein 1-like 1
UniProt Protein Name
Ganglioside-induced differentiation-associated protein 1-like 1
Protein Family
Ganglioside-induced differentiation-associated protein
UniProt Gene Name
GDAP1L1??[Similar Products]
UniProt Synonym Gene Names
GDAP1-L1??[Similar Products]
UniProt Entry Name
GD1L1_HUMAN
NCBI Summary for GDAP1L1
The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene. [provided by RefSeq, Feb 2012]
UniProt Comments for GDAP1L1
GDAP1L1: The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene. [provided by RefSeq, Feb 2012]
Chromosomal Location of Human Ortholog: 20q12
Precautions
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Disclaimer
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