Product Name
Transmembrane protein 43 (Tmem43), Recombinant Protein
Full Product Name
Recombinant Mouse Transmembrane protein 43 (Tmem43)
Product Gene Name
Tmem43 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-400aa; full length protein
Sequence
AANYSSTSSR KEHVKVTSEP QPGFLERLSE TSGGMFVGLM TFLLSFYLIF TNEGRALKTA TSLAEGLSLV VSPDSIHSVA PENEGRLVHI IGALRTSKLL SDPNYGVHLP AVKLRRHVEM YQWVETEESS EYTEDGQVKK ETKYSYNTEW RSEIVNSRNF DREIGHKNPS AMAVESFTAT APFVQIGRFF LSAGLIDKID NFKALSLAKL EDPHVDIIRR GDFFYHSENP KYPEVGDVRV SFSYAGLSSD DPDLGPAHVV TVIARQRGDQ LIPYSTKSGD TLLLLHHGDF SAEEVFRREQ KSNSMKTWGL RAAGWMAMFM GLNLMTRILY TLVDWFPVFR DLVNIGLKAF AFCVATSLTL LTVAAGWLFY RPLWAALIGC LALVPIIIAR TRVPAKKLE
3D Structure
ModBase 3D Structure for Q9DBS1
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Tmem43 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for Tmem43 recombinant protein
Transmembrane Protein
Application Notes for Tmem43 recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for Tmem43. It may not necessarily be applicable to this product.
NCBI Accession #
NP_083042.1
[Other Products]
NCBI GenBank Nucleotide #
NM_028766.2
[Other Products]
UniProt Primary Accession #
Q9DBS1
[Other Products]
UniProt Related Accession #
Q9DBS1[Other Products]
Molecular Weight
44,783 Da
NCBI Official Full Name
transmembrane protein 43
NCBI Official Synonym Full Names
transmembrane protein 43
NCBI Official Symbol
Tmem43??[Similar Products]
NCBI Official Synonym Symbols
LUMA; 1200015A22Rik
??[Similar Products]
NCBI Protein Information
transmembrane protein 43
UniProt Protein Name
Transmembrane protein 43
UniProt Synonym Protein Names
Protein LUMA
Protein Family
Transmembrane protein
UniProt Gene Name
Tmem43??[Similar Products]
UniProt Entry Name
TMM43_MOUSE
UniProt Comments for Tmem43
TMEM43: May have an important role in maintaining nuclear envelope structure by organizing protein complexes at the inner nuclear membrane. Required for retaining emerin at the inner nuclear membrane. Defects in TMEM43 are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5); also known as arrhythmogenic right ventricular cardiomyopathy (ARVC5). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall. Belongs to the TMEM43 family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen; Golgi apparatus; integral to membrane; integral to nuclear inner membrane; membrane; nuclear inner membrane; nucleus
Molecular Function: protein self-association
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
