Full Product Name
AGPAT7 Antibody
Product Gene Name
anti-AGPAT7 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q643R3
Concentration
1.0mg/ml (lot specific)
Other Notes
Small volumes of anti-AGPAT7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-AGPAT7 antibody
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for AGPAT7. It may not necessarily be applicable to this product.
NCBI Accession #
NP_705841.2
[Other Products]
NCBI GenBank Nucleotide #
NM_153613.2
[Other Products]
UniProt Primary Accession #
Q643R3
[Other Products]
UniProt Secondary Accession #
O43412; Q7Z4P4; Q8IUL7; Q8TB38; A8K2K8[Other Products]
UniProt Related Accession #
Q643R3[Other Products]
Molecular Weight
57,219 Da
NCBI Official Full Name
lysophospholipid acyltransferase LPCAT4
NCBI Official Synonym Full Names
lysophosphatidylcholine acyltransferase 4
NCBI Official Symbol
LPCAT4??[Similar Products]
NCBI Official Synonym Symbols
AYTL3; AGPAT7; LPEAT2; LPAAT-eta
??[Similar Products]
NCBI Protein Information
lysophospholipid acyltransferase LPCAT4
UniProt Protein Name
Lysophospholipid acyltransferase LPCAT4
UniProt Synonym Protein Names
1-acylglycerol-3-phosphate O-acyltransferase 7; 1-AGP acyltransferase 7; 1-AGPAT 7; 1-acylglycerophosphocholine O-acyltransferase (EC:2.3.1.23); 1-acylglycerophosphoserine O-acyltransferase (EC:2.3.1.n6); 1-alkenylglycerophosphoethanolamine O-acyltransferase (EC:2.3.1.121); 1-alkylglycerophosphocholine O-acetyltransferase (EC:2.3.1.67); Acyltransferase-like 3; Lysophosphatidylcholine acyltransferase 4; Lysophosphatidylethanolamine acyltransferase 2 (EC:2.3.1.n7); Plasmalogen synthase
UniProt Gene Name
LPCAT4??[Similar Products]
UniProt Synonym Gene Names
AGPAT7; AYTL3; LPEAT2; 1-AGP acyltransferase 7; 1-AGPAT 7??[Similar Products]
NCBI Summary for AGPAT7
Members of the 1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51) family, such as AGPAT7, catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a precursor in the biosynthesis of all glycerolipids. Both LPA and PA are involved in signal transduction (Ye et al., 2005 [PubMed 16243729]).[supplied by OMIM, May 2008]
UniProt Comments for AGPAT7
AGPAT7: Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates; converts lysophosphatidylethanolamine to phosphatidylethanolamine, lysophosphatidylcholine to phosphatidycholine, 1-alkenyl-lysophatidylethanolamine to 1- alkenyl-phosphatidylethanolamine, lysophosphatidylglycerol and alkyl-lysophosphatidylcholine to phosphatidylglycerol and alkyl- phosphatidylcholine, respectively. In contrast, has no lysophosphatidylinositol, glycerol-3-phosphate, diacylglycerol or lysophosphatidic acid acyltransferase activity. Prefers long chain acyl-CoAs (C16, C18) as acyl donors. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
Protein type: EC 2.3.1.121; EC 2.3.1.23; EC 2.3.1.67; EC 2.3.1.n6; EC 2.3.1.n7; Membrane protein, integral; Membrane protein, multi-pass; Transferase
Chromosomal Location of Human Ortholog: 15q14
Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; membrane
Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity; 2-acylglycerol-3-phosphate O-acyltransferase activity
Biological Process: phosphatidic acid biosynthetic process; phospholipid metabolic process; triacylglycerol biosynthetic process
Research Articles on AGPAT7
1. LPCAT4 is overexpressed and involved in the deregulation of PC(16:0/16:1) in colorectal cancer.
Precautions
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Disclaimer
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