Product Synonym Names
CDG2B; CWH41; DER7; GCS1
Product Gene Name
anti-MOGS antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q13724
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity purification
Immunogen
Recombinant protein of human MOGS
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of anti-MOGS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MOGS antibody
This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1, 2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene.
Applications Tested/Suitable for anti-MOGS antibody
Western Blot (WB)
Application Notes for anti-MOGS antibody
WB: 1:500-1:2000
NCBI/Uniprot data below describe general gene information for MOGS. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001139630.1
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NCBI GenBank Nucleotide #
NM_001146158.1
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UniProt Primary Accession #
Q13724
[Other Products]
UniProt Secondary Accession #
Q17RN9; Q8TCT5; A8K938; F5H6D0[Other Products]
UniProt Related Accession #
Q13724[Other Products]
NCBI Official Full Name
mannosyl-oligosaccharide glucosidase isoform 2
NCBI Official Synonym Full Names
mannosyl-oligosaccharide glucosidase
NCBI Official Symbol
MOGS??[Similar Products]
NCBI Official Synonym Symbols
DER7; GCS1; CDG2B; CWH41
??[Similar Products]
NCBI Protein Information
mannosyl-oligosaccharide glucosidase
UniProt Protein Name
Mannosyl-oligosaccharide glucosidase
UniProt Synonym Protein Names
Processing A-glucosidase I
Protein Family
Mannosyl-oligosaccharide glucosidase
UniProt Gene Name
MOGS??[Similar Products]
UniProt Synonym Gene Names
GCS1??[Similar Products]
NCBI Summary for MOGS
This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
UniProt Comments for MOGS
Cleaves the distal alpha 1,2-linked glucose residue from the Glc3Man9GlcNAc2 oligosaccharide precursor in a highly specific manner.
Research Articles on MOGS
1. A shortened immunoglobulin half-life was determined to be the mechanism underlying the hypogammaglobulinemia in congenital disorder of glycosylation type IIb (CDG-IIb).
Precautions
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Disclaimer
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