Product Name
mannosyl-oligosaccharide glucosidase (Mogs), Polyclonal Antibody
Full Product Name
Rabbit anti-human mannosyl-oligosaccharide glucosidase polyclonal Antibody
Product Synonym Names
mannosyl-oligosaccharide glucosidase; MOGS; GCS1
Product Gene Name
anti-Mogs antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-168007 / sc-130146 / sc-130146 / sc-134706
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-Mogs antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-Mogs antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for Mogs. It may not necessarily be applicable to this product.
NCBI Accession #
NP_065644.2
[Other Products]
NCBI GenBank Nucleotide #
NM_020619.2
[Other Products]
UniProt Secondary Accession #
Q9Z2W5[Other Products]
UniProt Related Accession #
Q80UM7[Other Products]
Molecular Weight
91,831 Da[Similar Products]
NCBI Official Full Name
mannosyl-oligosaccharide glucosidase
NCBI Official Synonym Full Names
mannosyl-oligosaccharide glucosidase
NCBI Official Symbol
Mogs??[Similar Products]
NCBI Official Synonym Symbols
Gcs1; AI181835; 1810017N02Rik
??[Similar Products]
NCBI Protein Information
mannosyl-oligosaccharide glucosidase; glucosidase 1; glucosidase I; glycoprotein-processing glucosidase I
UniProt Protein Name
Mannosyl-oligosaccharide glucosidase
UniProt Synonym Protein Names
Glucosidase 1; Glycoprotein-processing glucosidase I
Protein Family
Mannosyl-oligosaccharide glucosidase
UniProt Gene Name
Mogs??[Similar Products]
UniProt Synonym Gene Names
Gcs1??[Similar Products]
UniProt Entry Name
MOGS_MOUSE
UniProt Comments for Mogs
GCS1: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner. Defects in MOGS are the cause of type IIb congenital disorder of glycosylation (CDGIIb); also known as glucosidase I deficiency. CDGIIb is characterized by marked generalized hypotonia and hypomotility of the neonate, dysmorphic features, including a prominent occiput, short palpebral fissures, retrognathia, high arched palate, generalized edema, and hypoplastic genitalia. Symptoms of the infant included hepatomegaly, hypoventilation, feeding problems and seizures. The clinical course was progressive and the infant did not survive more than a few months. Belongs to the glycosyl hydrolase 63 family.
Protein type: Endoplasmic reticulum; EC 3.2.1.106; Glycan Metabolism - N-glycan biosynthesis; Hydrolase; Membrane protein, integral
Cellular Component: membrane; endoplasmic reticulum; integral to membrane
Molecular Function: mannosyl-oligosaccharide glucosidase activity; hydrolase activity; hydrolase activity, acting on glycosyl bonds; catalytic activity
Biological Process: metabolic process; oligosaccharide metabolic process
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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