Product Name
GCS1, Blocking Peptide
Full Product Name
GCS1 Peptide - N-terminal region
Product Gene Name
GCS1 blocking peptide
[Similar Products]
Product Synonym Gene Name
GCS1; CDG2B; MOGS[Similar Products]
GCS1 peptide (MBS3233255) is used for blocking the activity of GCS1 antibody (MBS3208293)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q13724
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of GCS1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
GCS1 blocking peptide
GCS1 is the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum.This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum.
Product Categories/Family for GCS1 blocking peptide
Peptide
Applications Tested/Suitable for GCS1 blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for GCS1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006293
[Other Products]
NCBI GenBank Nucleotide #
NM_006302
[Other Products]
UniProt Primary Accession #
Q13724
[Other Products]
UniProt Related Accession #
Q13724[Other Products]
NCBI Official Full Name
mannosyl-oligosaccharide glucosidase isoform 1
NCBI Official Synonym Full Names
mannosyl-oligosaccharide glucosidase
NCBI Official Symbol
MOGS??[Similar Products]
NCBI Official Synonym Symbols
DER7; GCS1; CDG2B; CWH41
??[Similar Products]
NCBI Protein Information
mannosyl-oligosaccharide glucosidase
UniProt Protein Name
Mannosyl-oligosaccharide glucosidase
UniProt Synonym Protein Names
Processing A-glucosidase I
Protein Family
Mannosyl-oligosaccharide glucosidase
UniProt Gene Name
MOGS??[Similar Products]
UniProt Synonym Gene Names
GCS1??[Similar Products]
UniProt Entry Name
MOGS_HUMAN
NCBI Summary for GCS1
This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Research Articles on GCS1
1. A shortened immunoglobulin half-life was determined to be the mechanism underlying the hypogammaglobulinemia in congenital disorder of glycosylation type IIb (CDG-IIb).
Precautions
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Disclaimer
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