Product Name
Neurokinin B (NKB), Polyclonal Antibody
Full Product Name
FITC-Linked Polyclonal Antibody to Neurokinin B (NKB)
Product Synonym Names
NK-B; TAC3; NKNB; ZNEUROK1; Neuromedin K; Tachykinin 3; Neurokinin Beta
Product Gene Name
anti-NKB antibody
[Similar Products]
Matching Pairs
Unconjugated Antibody: Neurokinin B (MBS2027440)
FITC Conjugated Antibody: Neurokinin B (NKB) (MBS2052471)
Matching Pairs
FITC Conjugated Antibody: Neurokinin B (NKB) (MBS2052471)
Immunogen: Neurokinin B (MBS2028998)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Concentration
200ug/ml (lot specific)
Immunogen
NKB (Gln29~Pro101)
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2027440
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customera??s specifications, please inquire.
Other Notes
Small volumes of anti-NKB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-NKB antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)
NCBI/Uniprot data below describe general gene information for NKB. It may not necessarily be applicable to this product.
NCBI Accession #
AAF76980.1
[Other Products]
UniProt Secondary Accession #
Q6IAG2; Q71BC6; Q71BC9[Other Products]
UniProt Related Accession #
Q9UHF0[Other Products]
Molecular Weight
11,358 Da
NCBI Official Full Name
neurokinin B
NCBI Official Synonym Full Names
tachykinin 3
NCBI Official Symbol
TAC3??[Similar Products]
NCBI Official Synonym Symbols
NKB; HH10; NKNB; PRO1155; ZNEUROK1
??[Similar Products]
NCBI Protein Information
tachykinin-3
UniProt Protein Name
Tachykinin-3
UniProt Synonym Protein Names
ZNEUROK1
UniProt Gene Name
TAC3??[Similar Products]
UniProt Synonym Gene Names
NKNB; NKB??[Similar Products]
NCBI Summary for NKB
This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded preproprotein is proteolytically processed to generate the mature peptide, which is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. This peptide is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
UniProt Comments for NKB
TAC3: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12q13.3
Cellular Component: extracellular region; extracellular space
Molecular Function: receptor binding
Biological Process: female pregnancy
Disease: Hypogonadotropic Hypogonadism 10 With Or Without Anosmia
Research Articles on NKB
1. mutations in TAC and TACR3 are not a common cause for ICPP.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
