Full Product Name
Anti-BCAS4 Antibody
Product Synonym Names
Breast carcinoma-amplified sequence 4
Product Gene Name
anti-BCAS4 antibody
[Similar Products]
Antibody/Peptide Pairs
BCAS4 peptide (MBS8243967) is used for blocking the activity of BCAS4 antibody (MBS8241681)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8TDM0
Specificity
Recognizes endogenous levels of BCAS4 protein.
Purity/Purification
The antibody was purified by affinity chromatography.
Form/Format
Liquid in PBS, pH 7.3, 0.2% BSA, and 0.02% Sodium Azide.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BCAS4. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-BCAS4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-BCAS4 antibody
Rabbit polyclonal antibody to BCAS4
Applications Tested/Suitable for anti-BCAS4 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-BCAS4 antibody
Western Blot: (1/500 - 1/1000); Immunohistochemistry: (1/100 - 1/200)
Western Blot (WB) of anti-BCAS4 antibody
Western blot analysis of BCAS4 expression in A431 (A), K562 (B) whole cell lysates.

Immunohistochemistry (IHC) of anti-BCAS4 antibody
Immunohistochemical analysis of BCAS4 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

NCBI/Uniprot data below describe general gene information for BCAS4. It may not necessarily be applicable to this product.
NCBI Accession #
Q8TDM0.1
[Other Products]
UniProt Primary Accession #
Q8TDM0
[Other Products]
UniProt Secondary Accession #
Q5TD52; Q5TD53; Q5TD54; Q5U5K7; Q5XKE8; Q8IXI7; Q8NEZ6; Q8TDL9; Q9NX13; Q9Y511[Other Products]
UniProt Related Accession #
Q8TDM0[Other Products]
Molecular Weight
22,495 Da
NCBI Official Full Name
Breast carcinoma-amplified sequence 4
NCBI Official Synonym Full Names
breast carcinoma amplified sequence 4
NCBI Official Symbol
BCAS4??[Similar Products]
NCBI Official Synonym Symbols
CNOL
??[Similar Products]
NCBI Protein Information
breast carcinoma-amplified sequence 4
UniProt Protein Name
Breast carcinoma-amplified sequence 4
Protein Family
Breast carcinoma-amplified sequence
UniProt Gene Name
BCAS4??[Similar Products]
UniProt Entry Name
BCAS4_HUMAN
UniProt Comments for BCAS4
BCAS4: A chromosomal aberration involving BCAS4 has been found in some breast carcinoma cell lines. Translocation t(17;20)(q23;q13) with BCAS3. Belongs to the cappuccino family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Oncoprotein
Chromosomal Location of Human Ortholog: 20q13.13
Biological Process: intracellular transport
Research Articles on BCAS4
1. BCAS3 (17q23) and BCAS4 (20q13) undergo amplification, overexpression, and fusion in breast cancer.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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