Full Product Name
DAOA Rabbit Polyclonal
Product Gene Name
anti-DAOA antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Immunogen
D-amino acid oxidase activator
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-DAOA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-DAOA antibody
ELISA (EIA), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for DAOA. It may not necessarily be applicable to this product.
NCBI Accession #
NP_758958.3
[Other Products]
NCBI GenBank Nucleotide #
NM_172370.4
[Other Products]
UniProt Secondary Accession #
Q0VAE6; Q5VX59; Q86Y17; Q8IWM4; A6NKG7[Other Products]
UniProt Related Accession #
P59103[Other Products]
Molecular Weight
14,719 Da
NCBI Official Full Name
D-amino acid oxidase activator isoform 1
NCBI Official Synonym Full Names
D-amino acid oxidase activator
NCBI Official Symbol
DAOA??[Similar Products]
NCBI Official Synonym Symbols
LG72; SG72
??[Similar Products]
NCBI Protein Information
D-amino acid oxidase activator
UniProt Protein Name
D-amino acid oxidase activator
UniProt Synonym Protein Names
Protein G72
Protein Family
D-amino acid oxidase activator
UniProt Gene Name
DAOA??[Similar Products]
UniProt Synonym Gene Names
G72??[Similar Products]
UniProt Entry Name
DAOA_HUMAN
NCBI Summary for DAOA
This gene encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Mar 2011]
UniProt Comments for DAOA
DAOA: Seems to activate D-amino acid oxidase. 4 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 13q33.2|13q34
Cellular Component: Golgi apparatus; mitochondrion; perinuclear region of cytoplasm
Molecular Function: enzyme activator activity; enzyme binding
Biological Process: positive regulation of catalytic activity
Disease: Schizophrenia
Research Articles on DAOA
1. Report in silico analysis of DAOA for the design of inhibitors for treatment of schizophrenia.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
