Rabbit Polyclonal (IgG) to Human DAOA; Human DAOA; D-amino acid oxidase activator; G72; LG72; Protein G72; SG72; G72 transcript

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

Human DAOA

Caprylic acid and ammonium sulfate precipitation

PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.

1 mg/ml (lot specific)

Long term: -20 degree C
Short term: 4 degree C
Avoid repeat freeze-thaw cycles

Small volumes of anti-DAOA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

DAOA Antibody, D-amino acid oxidase activator Antibody, G72 Antibody, LG72 Antibody, Protein G72 Antibody, SG72 Antibody, G72 transcript Antibody Description: DAOA is a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder.

Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)

IHC-P (10 ug/ml)

Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

14,719 Da

D-amino acid oxidase activator

D-amino acid oxidase activator

D-amino acid oxidase activator

G72??[Similar Products]

DAOA_HUMAN

This gene encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Mar 2011]

DAOA: Seems to activate D-amino acid oxidase. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 13q33.2|13q34

Cellular Component: Golgi apparatus; mitochondrion; perinuclear region of cytoplasm

Molecular Function: enzyme activator activity; enzyme binding

Biological Process: positive regulation of catalytic activity

Disease: Schizophrenia

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