Product Name
D-amino acid oxidase activator (DAOA), Polyclonal Antibody
Full Product Name
Rabbit anti-human D-amino acid oxidase activator polyclonal Antibody, Biotin conjugated
Product Synonym Names
Protein G72 DAOA G72
Product Gene Name
anti-DAOA antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P59103
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Immunogen
Recombinant human D-amino acid oxidase activator protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-46118 / sc-66895
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-DAOA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-DAOA antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for DAOA. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001155284.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001161812.1
[Other Products]
UniProt Primary Accession #
P59103
[Other Products]
UniProt Secondary Accession #
Q0VAE6; Q5VX59; Q86Y17; Q8IWM4; A6NKG7[Other Products]
UniProt Related Accession #
P59103[Other Products]
Molecular Weight
14,719 Da[Similar Products]
NCBI Official Full Name
D-amino acid oxidase activator isoform 2
NCBI Official Synonym Full Names
D-amino acid oxidase activator
NCBI Official Symbol
DAOA??[Similar Products]
NCBI Official Synonym Symbols
LG72; SG72
??[Similar Products]
NCBI Protein Information
D-amino acid oxidase activator
UniProt Protein Name
D-amino acid oxidase activator
UniProt Synonym Protein Names
Protein G72
Protein Family
D-amino acid oxidase activator
UniProt Gene Name
DAOA??[Similar Products]
UniProt Synonym Gene Names
G72??[Similar Products]
UniProt Entry Name
DAOA_HUMAN
NCBI Summary for DAOA
This gene encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Mar 2011]
UniProt Comments for DAOA
DAOA: Seems to activate D-amino acid oxidase. 4 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 13q33.2|13q34
Cellular Component: Golgi apparatus; mitochondrion; perinuclear region of cytoplasm
Molecular Function: enzyme activator activity; enzyme binding
Biological Process: positive regulation of catalytic activity
Disease: Schizophrenia
Research Articles on DAOA
1. There were no regions with significantly reduced FA values in homozygous risk allele carriers.
Precautions
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Disclaimer
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