Probable cation-transporting ATPase 13A2; Atp13a2

For Research Use Only. Not for use in diagnostic procedures.

For long term storage, please store the entire kit at -20 degree C.

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Small volumes of Atp13a2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS2884648 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Probable cation-transporting ATPase 13A2 (Atp13a2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Atp13a2. The ELISA analytical biochemical technique of the MBS2884648 kit is based on Atp13a2 antibody-Atp13a2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Atp13a2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Atp13a2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

126,443 Da

ATPase type 13A2

probable cation-transporting ATPase 13A2

Probable cation-transporting ATPase 13A2

AT132_MOUSE

ATP13A2: May play a role in intracellular cation homeostasis and the maintenance of neuronal integrity. Expressed in brain; protein levels are markedly increased in brain from subjects with Parkinson disease and subjects with dementia with Lewy bodies. Detected in pyramidal neurons located throughout the cingulate cortex. In the substantia nigra, it is found in neuromelanin- positive dopaminergic neurons. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; Transporter; Transporter, ion channel; Membrane protein, multi-pass; Membrane protein, integral; EC 3.6.3.-

Cellular Component: integral to membrane; integral to plasma membrane; intracellular membrane-bound organelle; lysosomal membrane; lysosome; membrane; vesicle membrane

Molecular Function: ATP binding; ATPase activity; cation-transporting ATPase activity; hydrolase activity; metal ion binding; nucleotide binding

Biological Process: cation transport; cellular calcium ion homeostasis

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