CD25 Purified (Clone OX-39) (mouse IgG1); Purified Anti-Rat CD25 (IL-2R) Monoclonal Antibody

For Research Use Only. Not for use in diagnostic procedures.

Monoclonal

Mouse IgG1

MRC OX-39

Mouse

CD25 (IL-2Ra) (Rat CD25 (IL-2 Receptor))

Purified (Purified Ig buffered in PBS and 0.02% NaN3. (Purified from ascitic fluid via Protein G Chromatography))

Antibody Concentration: 1.0 mg/ml (lot specific)

Store at 4 degree C. For long term storage, aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.

Small volumes of anti-CD25 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

anti-rat CD25 (IL-2R) monoclonal antibody recognizes the smaller (alpha subunit) 55kD chain of the IL-2 receptor found on activated rat T cells, thymic dendritic cells but not resting lymphocytes (1). MBS520076 binds to the rat interleukin-2 receptor designated CD25 and has proven to be an important marker for activated T cells. (2) This clone is reported to work with frozen and paraffin sections (3).

Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS), Functional Assay (FA)

17,946 Da

Peripheral myelin protein 22

Cd25; Pmp-22; PMP-22; SAG??[Similar Products]

PMP22_RAT

Function: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.

Subcellular location: Cell membrane; Multi-pass membrane protein

By similarity.

Tissue specificity: Found exclusively in the peripheral nervous system. Present in both myelinating and nonmyelinating Schwann cells. Found in the tumors of Schwann cell lineage where axons are present (neurofibromas) but not where axons are absent (schwannomas). Ref.4

Developmental stage: Levels increase between embryonic day 21 (E21) and postnatal day 0 (PND0) and then gradually increase up to PND15. There is a slight increase between PND15 and *****hood. Ref.4

Induction: Strongly down-regulated in the initial phase after sciatic nerve injury.

Sequence similarities: Belongs to the PMP-22/EMP/MP20 family.

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