Product Name
Inactive serine/threonine-protein kinase TEX14 (Tex14), Recombinant Protein
Full Product Name
Recombinant Mouse Inactive serine/threonine-protein kinase TEX14 (Tex14) , partial
Product Gene Name
Tex14 recombinant protein
[Similar Products]
Product Synonym Gene Name
Tex14[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q7M6U3
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Tex14 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Tex14 recombinant protein
This gene is similar to a mouse gene that is expressed in the testis.
NCBI/Uniprot data below describe general gene information for Tex14. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001186222.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001199293.1
[Other Products]
UniProt Primary Accession #
Q7M6U3
[Other Products]
UniProt Secondary Accession #
Q3UT36; Q5NC10; Q5NC11; Q8CGK1; Q8CGK2; Q99MV8; B2KGL0[Other Products]
UniProt Related Accession #
Q7M6U3[Other Products]
Molecular Weight
138,851 Da
NCBI Official Full Name
inactive serine/threonine-protein kinase TEX14 isoform a
NCBI Official Synonym Full Names
testis expressed gene 14
NCBI Official Symbol
Tex14??[Similar Products]
NCBI Official Synonym Symbols
C85585
??[Similar Products]
NCBI Protein Information
inactive serine/threonine-protein kinase TEX14
UniProt Protein Name
Inactive serine/threonine-protein kinase TEX14
UniProt Synonym Protein Names
Testis-expressed sequence 14; Testis-expressed sequence 14 protein
Protein Family
Inactive serine/threonine-protein kinase
UniProt Gene Name
Tex14??[Similar Products]
UniProt Comments for Tex14
Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro.
Research Articles on Tex14
1. Data indicate that testis-expressed gene 14 (TEX14) is expressed in germ cells.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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