Product Name
Potassium voltage-gated channel subfamily E member 1 (KCNE1), Recombinant Protein
Full Product Name
Recombinant Pongo abelii Potassium voltage-gated channel subfamily E member 1 (KCNE1), partial
Product Gene Name
KCNE1 recombinant protein
[Similar Products]
Product Synonym Gene Name
KCNE1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
67-129
Sequence
RSKK LEHSNDPFNV YIESDAWQEK DKAYVQARVL KSYRACYVVE NHLAVEQPNT HLPGTKPSP
3D Structure
ModBase 3D Structure for Q5R8Q2
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Pongo abelii (Sumatran orangutan)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of KCNE1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for KCNE1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001126076.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001132604.1
[Other Products]
UniProt Primary Accession #
Q5R8Q2
[Other Products]
UniProt Related Accession #
Q5R8Q2[Other Products]
Molecular Weight
14,568 Da
NCBI Official Full Name
potassium voltage-gated channel subfamily E member 1
NCBI Official Symbol
KCNE1??[Similar Products]
NCBI Protein Information
potassium voltage-gated channel subfamily E member 1
UniProt Protein Name
Potassium voltage-gated channel subfamily E member 1
Protein Family
Potassium voltage-gated channel subfamily
UniProt Gene Name
KCNE1??[Similar Products]
UniProt Comments for KCNE1
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr).
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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