Full Product Name
GJA9 antibody - middle region
Product Gene Name
anti-GJA9 antibody
[Similar Products]
Product Synonym Gene Name
CX58; CX59; GJA10; MGC50985[Similar Products]
Antibody/Peptide Pairs
GJA9 peptide (MBS3228199) is used for blocking the activity of GJA9 antibody (MBS3203227)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: IDGENNMRQS PQTVFSLPAN CDWKPRWLRA TWGSSTEHEN RGSPPKGNLK
3D Structure
ModBase 3D Structure for P57773
Species Reactivity
Dog, Human
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Dog: 86%; Human: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human GJA9
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-GJA9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GJA9 antibody
This is a rabbit polyclonal antibody against GJA9. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: Connexins, such as GJA9, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.Connexins, such as GJA9, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-612 BI463634.1 7-618 613-1929 AF271261.1 585-1901 1930-2331 BU689816.1 1-402 c
Product Categories/Family for anti-GJA9 antibody
Polyclonal; Membrane Protein;
Applications Tested/Suitable for anti-GJA9 antibody
Western Blot (WB)
Western Blot (WB) of anti-GJA9 antibody
Host: Rabbit
Target Name: GJA9
Sample Type: Human Adult Placenta
Antibody Dilution: 1.0ug/ml

Western Blot (WB) of anti-GJA9 antibody
Host: Rabbit
Target Name: GJA9
Sample Type: Human Fetal Liver
Antibody Dilution: 1.0ug/ml

Western Blot (WB) of anti-GJA9 antibody
Host: Rabbit
Target Name: GJA9
Sample Type: Human Fetal Muscle
Antibody Dilution: 1.0ug/ml

Western Blot (WB) of anti-GJA9 antibody
WB Suggested Anti-GJA9 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human brain

NCBI/Uniprot data below describe general gene information for GJA9. It may not necessarily be applicable to this product.
NCBI Accession #
NP_110399
[Other Products]
NCBI GenBank Nucleotide #
NM_030772
[Other Products]
UniProt Primary Accession #
P57773
[Other Products]
UniProt Related Accession #
P57773[Other Products]
NCBI Official Full Name
gap junction alpha-9 protein
NCBI Official Synonym Full Names
gap junction protein alpha 9
NCBI Official Symbol
GJA9??[Similar Products]
NCBI Official Synonym Symbols
CX58; CX59; GJA10
??[Similar Products]
NCBI Protein Information
gap junction alpha-9 protein
UniProt Protein Name
Gap junction alpha-9 protein
UniProt Synonym Protein Names
Connexin-58; Cx58; Connexin-59; Cx59; Gap junction alpha-10 protein
Protein Family
Gap junction alpha-9 protein
UniProt Gene Name
GJA9??[Similar Products]
UniProt Synonym Gene Names
GJA10; Cx58; Cx59??[Similar Products]
UniProt Entry Name
CXA9_HUMAN
NCBI Summary for GJA9
Connexins, such as GJA9, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008]
UniProt Comments for GJA9
GJA9: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Alpha-type (group II) subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p34
Cellular Component: connexon complex; integral to membrane
Biological Process: cell communication
Research Articles on GJA9
1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Precautions
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Disclaimer
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