Product Name
Alcohol dehydrogenase 1C (ADH1C), Recombinant Protein
Full Product Name
Recombinant Human Alcohol dehydrogenase 1C (ADH1C)
Product Synonym Names
Alcohol dehydrogenase 1C; EC=1.1.1.1; Alcohol dehydrogenase subunit gamma
Product Gene Name
ADH1C recombinant protein
[Similar Products]
Product Synonym Gene Name
ADH1C; ADH3[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-375aa; Full Length
Sequence
STAGKVIKCK AAVLWELKKP FSIEEVEVAP PKAHEVRIKM VAAGICRSDE HVVSGNLVTP LPVILGHEAA GIVESVGEGV TTVKPGDKVI PLFTPQCGKC RICKNPESNY CLKNDLGNPR GTLQDGTRRF TCSGKPIHHF VGVSTFSQYT VVDENAVAKI DAASPLEKVC LIGCGFSTGY GSAVKVAKVT PGSTCAVFGL GGVGLSVVMG CKAAGAARII AVDINKDKFA KAKELGATEC INPQDYKKPI QEVLKEMTDG GVDFSFEVIG RLDTMMASLL CCHEACGTSV IVGVPPDSQN LSINPMLLLT GRTWKGAIFG GFKSKESVPK LVADFMAKKF SLDALITNIL PFEKINEGFD LLRSGKSIRT VLTF
3D Structure
ModBase 3D Structure for P00326
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ADH1C recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for ADH1C recombinant protein
Signal Transduction
SDS-PAGE of ADH1C recombinant protein

(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for ADH1C. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000660.1
[Other Products]
NCBI GenBank Nucleotide #
NM_000669.4
[Other Products]
UniProt Primary Accession #
P00326
[Other Products]
UniProt Secondary Accession #
Q4PJ18; Q5WRV0; Q6LBW4; Q6NWV0; Q6NZA7[Other Products]
UniProt Related Accession #
P00326[Other Products]
Molecular Weight
39,868 Da
NCBI Official Full Name
alcohol dehydrogenase 1C
NCBI Official Synonym Full Names
alcohol dehydrogenase 1C (class I), gamma polypeptide
NCBI Official Symbol
ADH1C??[Similar Products]
NCBI Official Synonym Symbols
ADH3
??[Similar Products]
NCBI Protein Information
alcohol dehydrogenase 1C; ADH, gamma subunit; aldehyde reductase; alcohol dehydrogenase 3 (class I), gamma polypeptide
UniProt Protein Name
Alcohol dehydrogenase 1C
UniProt Synonym Protein Names
Alcohol dehydrogenase subunit gamma
Protein Family
Alcohol dehydrogenase
UniProt Gene Name
ADH1C??[Similar Products]
UniProt Synonym Gene Names
ADH3??[Similar Products]
UniProt Entry Name
ADH1G_HUMAN
NCBI Summary for ADH1C
This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq, Jul 2008]
UniProt Comments for ADH1C
ADH1C: class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq, Jul 2008]
Protein type: Lipid Metabolism - fatty acid; Amino Acid Metabolism - tyrosine; Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Oxidoreductase; Xenobiotic Metabolism - metabolism by cytochrome P450; Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 1.1.1.1; Mitochondrial
Chromosomal Location of Human Ortholog: 4q23
Cellular Component: cytosol
Molecular Function: zinc ion binding; alcohol dehydrogenase activity
Biological Process: xenobiotic metabolic process; ethanol oxidation
Disease: Alcohol Dependence; Parkinson Disease, Late-onset
Research Articles on ADH1C
1. Alcohol dehydrogenase (ADH)1B and ADH1C are jointly associated with alcohol use disorders, but not consumption.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.