Product Name
CHST3, Blocking Peptide
Full Product Name
CHST3 Peptide - C-terminal region
Product Gene Name
CHST3 blocking peptide
[Similar Products]
Product Synonym Gene Name
HSD; C6ST; C6ST1[Similar Products]
CHST3 peptide (MBS3247291) is used for blocking the activity of CHST3 antibody (MBS3222623)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
Synthetic peptide located within the following region: QAAHDGSGIY STQKNSSEQF EKWRFSMPFK LAQVVQAACG PAMRLFGYKL
3D Structure
ModBase 3D Structure for Q7LGC8
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of CHST3 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CHST3 blocking peptide
This is a synthetic peptide designed for use in combination with anti- CHST3 Antibody, made
Target Description: This gene encodes an enzyme which catalyzes the sulfation of chondroitin, a proteoglycan found in the extracellular matrix and most cells which is involved in cell migration and differentiation. Mutations in this gene are associated with spondylepiphyseal dysplasia and humerospinal dysostosis.
Product Categories/Family for CHST3 blocking peptide
Peptide
NCBI/Uniprot data below describe general gene information for CHST3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_004264.2
[Other Products]
NCBI GenBank Nucleotide #
NM_004273.4
[Other Products]
UniProt Primary Accession #
Q7LGC8
[Other Products]
UniProt Related Accession #
Q7LGC8[Other Products]
NCBI Official Full Name
carbohydrate sulfotransferase 3
NCBI Official Synonym Full Names
carbohydrate sulfotransferase 3
NCBI Official Symbol
CHST3??[Similar Products]
NCBI Official Synonym Symbols
HSD; C6ST; C6ST1
??[Similar Products]
NCBI Protein Information
carbohydrate sulfotransferase 3
UniProt Protein Name
Carbohydrate sulfotransferase 3
UniProt Synonym Protein Names
Chondroitin 6-O-sulfotransferase 1; C6ST-1; Chondroitin 6-sulfotransferase; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0; GST-0
Protein Family
Carbohydrate sulfotransferase
UniProt Gene Name
CHST3??[Similar Products]
UniProt Synonym Gene Names
C6ST-1; GST-0??[Similar Products]
NCBI Summary for CHST3
This gene encodes an enzyme which catalyzes the sulfation of chondroitin, a proteoglycan found in the extracellular matrix and most cells which is involved in cell migration and differentiation. Mutations in this gene are associated with spondylepiphyseal dysplasia and humerospinal dysostosis. [provided by RefSeq, Mar 2009]
UniProt Comments for CHST3
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues of keratan sulfate, another glycosaminoglycan, and the Gal residues in sialyl N-acetyllactosamine (sialyl LacNAc) oligosaccharides. May play a role in the maintenance of naive T-lymphocytes in the spleen.
Research Articles on CHST3
1. We describe three consanguineous Indian families with a distinct form of spondyloepiphyseal dysplasia (SED Omani type). It is an autosomal recessive disorder due to mutation in CHST3 gene.
Precautions
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Disclaimer
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