Product Name
Cancer Antigen 125 (MUC16), Protein
Popular Item
Full Product Name
Cancer Antigen 125 (CA-125), Human
Product Synonym Names
CA-125; Carbohydrate Antigen 125; Mucin-16
Product Gene Name
MUC16 protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8WXI7
Purity/Purification
> 95% (SDS-PAGE)
Form/Format
Solution in phosphate buffered saline pH 7.4 with 3% sucrose and 0.05% sodium azide
Source
Human Ascites Fluid,adenocarcinoma
Appearance
Clear and colorless
Handling
Handle as a potentially hazardous substance.
Recovery
Microfuge the vial before drawing from container.
Preparation and Storage
Store at -20°C.
Avoid freeze/thaws.
Shipping: Ships with Dry Ice.
Other Notes
Small volumes of MUC16 protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
MUC16 protein
MyBioSource is the leading supplier of Cancer Antigen 125 (CA-125, MUCIN 16) for ovarian cancer research and biomarkers for manufacturing.
Custom preparations, technical support, bulk quantities and aliquoting available.
Cancer Antigen 125 (CA125) is a surface antigen associated with epithelial ovarian cancer. In serum, CA125 is associated with a high molecular weight glycoprotein. Published studies have indicated that elevated serum CA125 levels can be found in individuals with serious endometroid, clear-cell and undifferentiated ovarian carcinoma.
Associated Cancer Types: Ovarian Cancer Endometrial Cancer Fallopian Tube Cancer Lung Cancer Breast Cancer Gastrointestinal Cancer
Product Categories/Family for MUC16 protein
Proteins; Antigens; Enzymes; Standards/controls; Native Proteins; Cancer Antigen 125 (ca-125; Muc16)
NCBI/Uniprot data below describe general gene information for MUC16. It may not necessarily be applicable to this product.
NCBI Accession #
Q8WXI7.2
[Other Products]
UniProt Primary Accession #
Q8WXI7
[Other Products]
UniProt Secondary Accession #
Q6ZQW5; Q96RK2[Other Products]
UniProt Related Accession #
Q8WXI7[Other Products]
NCBI Official Full Name
Mucin-16
NCBI Official Synonym Full Names
mucin 16, cell surface associated
NCBI Official Symbol
MUC16??[Similar Products]
NCBI Official Synonym Symbols
CA125
??[Similar Products]
NCBI Protein Information
mucin-16; CA125 ovarian cancer antigen; ovarian carcinoma antigen CA125; ovarian cancer-related tumor marker CA125
UniProt Protein Name
Mucin-16
UniProt Synonym Protein Names
Ovarian cancer-related tumor marker CA125; CA-125; Ovarian carcinoma antigen CA125
UniProt Gene Name
MUC16??[Similar Products]
UniProt Synonym Gene Names
CA125; MUC-16; CA-125??[Similar Products]
UniProt Entry Name
MUC16_HUMAN
UniProt Comments for MUC16
MUC16: Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
Protein type: Cell adhesion; Membrane protein, peripheral; Membrane protein, integral
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: extracellular space; extrinsic to membrane; Golgi lumen; plasma membrane; integral to membrane; vesicle
Molecular Function: protein binding
Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; cell adhesion; post-translational protein modification
Research Articles on MUC16
1. Serum NSE and CA125 concentrations would provide valuable clinical information to assess disease severity in silicosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
