Full Product Name
ARHGEF6 Antibody
Product Gene Name
anti-ARHGEF6 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q15052
Other Notes
Small volumes of anti-ARHGEF6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Western Blot (WB) of anti-ARHGEF6 antibody
Western blot analysis ARHGEF6 using K562 whole cell lysates
NCBI/Uniprot data below describe general gene information for ARHGEF6. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001293106.1
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NCBI GenBank Nucleotide #
NM_001306177.1
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UniProt Primary Accession #
Q15052
[Other Products]
UniProt Secondary Accession #
Q15396; Q5JQ66; Q7Z3W1; Q86XH0; A6NMW9; A8K6S7; B1AL37[Other Products]
UniProt Related Accession #
Q15052[Other Products]
Molecular Weight
70,791 Da
NCBI Official Full Name
rho guanine nucleotide exchange factor 6 isoform 2
NCBI Official Synonym Full Names
Rac/Cdc42 guanine nucleotide exchange factor 6
NCBI Official Symbol
ARHGEF6??[Similar Products]
NCBI Official Synonym Symbols
PIXA; COOL2; MRX46; Cool-2; alphaPIX; alpha-PIX
??[Similar Products]
NCBI Protein Information
rho guanine nucleotide exchange factor 6
UniProt Protein Name
Rho guanine nucleotide exchange factor 6
UniProt Synonym Protein Names
Alpha-Pix; COOL-2; PAK-interacting exchange factor alpha; Rac/Cdc42 guanine nucleotide exchange factor 6
Protein Family
Rho guanine nucleotide exchange factor
UniProt Gene Name
ARHGEF6??[Similar Products]
UniProt Synonym Gene Names
COOL2; KIAA0006; PIXA??[Similar Products]
NCBI Summary for ARHGEF6
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific cognitive disability. [provided by RefSeq, Jul 2008]
UniProt Comments for ARHGEF6
Acts as a RAC1 guanine nucleotide exchange factor (GEF).
Research Articles on ARHGEF6
1. we discuss recent findings in key physiological systems that exemplify current understanding of the function of this important regulatory complex. Further, we draw attention to gaps in crucial information that remain to be filled to allow a better understanding of the many roles of the GIT-PIX complex in health and disease
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
