Full Product Name
Rat Lman1 Polyclonal Antibody
Product Synonym Names
Ergic53; ER-Golgi intermediate compartment 53 kDa protein; Lectin mannose-binding 1; p58
Product Gene Name
anti-LMAN1 antibody
[Similar Products]
Matching Pairs
Antibody: LMAN1 (MBS2901373)
Antigen: ERGIC-53 (MBS2889655)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P49257
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Immunogen Affinity Purified
Form/Format
Liquid; 0.1MxPBS, 50% Glycerol, pH7.5
Concentration
200 ug/ml (lot specific)
Immunogen
Recombinant Human Lman1 Protein
Preparation and Storage
Store at 4 degree C for frequent use. Store at -20 degree C to -70 degree C for 6 months.
Other Notes
Small volumes of anti-LMAN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-LMAN1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for LMAN1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005561
[Other Products]
NCBI GenBank Nucleotide #
NP_005561.1
[Other Products]
UniProt Primary Accession #
P49257
[Other Products]
UniProt Related Accession #
P49257[Other Products]
NCBI Official Full Name
protein ERGIC-53
NCBI Official Synonym Full Names
lectin, mannose binding 1
NCBI Official Symbol
LMAN1??[Similar Products]
NCBI Official Synonym Symbols
MR60; gp58; F5F8D; FMFD1; MCFD1; ERGIC53; ERGIC-53
??[Similar Products]
NCBI Protein Information
protein ERGIC-53
UniProt Protein Name
Protein ERGIC-53
UniProt Synonym Protein Names
ER-Golgi intermediate compartment 53 kDa protein; Gp58; Intracellular mannose-specific lectin MR60; Lectin mannose-binding 1
UniProt Gene Name
LMAN1??[Similar Products]
UniProt Synonym Gene Names
ERGIC53; F5F8D??[Similar Products]
UniProt Entry Name
LMAN1_HUMAN
NCBI Summary for LMAN1
The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency. [provided by RefSeq, Jul 2015]
Research Articles on LMAN1
1. that Multiple coagulation factor deficiency protein 2 promotes cancer metastasis by regulating lectin mannose binding 1 and level of galactoside-binding soluble 3 binding protein expression levels
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
