Product Name
SYNPO2, Polyclonal Antibody
Full Product Name
SYNPO2 antibody - C-terminal region
Product Gene Name
anti-SYNPO2 antibody
[Similar Products]
Product Synonym Gene Name
DKFZp686G051[Similar Products]
Antibody/Peptide Pairs
SYNPO2 peptide (MBS3241458) is used for blocking the activity of SYNPO2 antibody (MBS3216559)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: FTFKEPKVSP NPELLSLLQN SEGKRGTGAG GDSGPEEDYL SLGAEACNFM
3D Structure
ModBase 3D Structure for Q9UMS6
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 79%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 100%
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-SYNPO2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SYNPO2 antibody
This is a rabbit polyclonal antibody against SYNPO2. It was validated on Western Blot
Target Description: SYNPO2 has an actin-binding and actin-bundling activity.
Product Categories/Family for anti-SYNPO2 antibody
Polyclonal; Transcription Factor; Cell Biology;
Applications Tested/Suitable for anti-SYNPO2 antibody
Western Blot (WB)
Western Blot (WB) of anti-SYNPO2 antibody
WB Suggested Anti-SYNPO2 Antibody
Titration: 1.0 ug/ml
Positive Control: 721_B Whole Cell
NCBI/Uniprot data below describe general gene information for SYNPO2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001122405
[Other Products]
NCBI GenBank Nucleotide #
NM_001128933
[Other Products]
UniProt Primary Accession #
Q9UMS6
[Other Products]
UniProt Related Accession #
Q9UMS6[Other Products]
NCBI Official Full Name
synaptopodin-2 isoform b
NCBI Official Synonym Full Names
synaptopodin 2
NCBI Official Symbol
SYNPO2??[Similar Products]
NCBI Protein Information
synaptopodin-2
UniProt Protein Name
Synaptopodin-2
UniProt Synonym Protein Names
Genethonin-2; Myopodin
Protein Family
Synaptopodin
UniProt Gene Name
SYNPO2??[Similar Products]
UniProt Entry Name
SYNP2_HUMAN
UniProt Comments for SYNPO2
SYNPO2: Has an actin-binding and actin-bundling activity. Belongs to the synaptopodin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 4q26
Cellular Component: focal adhesion; Z disc; nucleus; actin cytoskeleton
Molecular Function: protein binding; actin binding; muscle alpha-actinin binding
Research Articles on SYNPO2
1. These findings uncover a suppressive role of SYNPO2 in triple-negative breast cancer (TNBC) metastasis via inhibition of YAP/TAZ, and suggest that SYNPO2 might provide a potential prognosis marker and novel therapeutic strategy.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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