Protein ERGIC-53; ER-Golgi intermediate compartment 53 kDa protein; Lectin mannose-binding 1; p58; Lman1; Ergic53

For Research Use Only. Not for use in diagnostic procedures.

For long term storage, please store the entire kit at -20 degree C.

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Small volumes of Lman1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS2880274 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ERGIC-53 (Lman1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Lman1. The ELISA analytical biochemical technique of the MBS2880274 kit is based on Lman1 antibody-Lman1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Lman1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Lman1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

57,957 Da

lectin, mannose-binding, 1

protein ERGIC-53

Protein ERGIC-53

Ergic53??[Similar Products]

LMAN1_RAT

calcium-dependent lectin; involved in glycoprotein export from the ER [RGD, Feb 2006]

LMAN1: Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. Defects in LMAN1 are THE cause of factor V and factor VIII combined deficiency type 1 (F5F8D1); also known as multiple coagulation factor deficiency I (MCFD1). F5F8D1 is an autosomal recessive blood coagulation disorder characterized by bleeding symptoms similar to those in hemophilia or parahemophilia, that are caused by single deficiency of FV or FVIII, respectively. The most common symptoms are epistaxis, menorrhagia, and excessive bleeding during or after trauma. Plasma levels of coagulation factors V and VIII are in the range of 5 to 30% of normal.

Protein type: Membrane protein, integral

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; ER to Golgi transport vesicle; ER-Golgi intermediate compartment; ER-Golgi intermediate compartment membrane; Golgi apparatus; Golgi membrane; integral to membrane; intracellular membrane-bound organelle; membrane; sarcomere

Molecular Function: calcium ion binding; identical protein binding; mannose binding

Biological Process: endoplasmic reticulum organization and biogenesis; ER to Golgi vesicle-mediated transport; Golgi organization and biogenesis; protein exit from endoplasmic reticulum; protein transport

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