Cholecystokinin receptor type A; CCK-A receptor; CCK-AR; Cholecystokinin-1 receptor; CCK1-R; Cckar

For Research Use Only. Not for use in diagnostic procedures.

The synthetic peptide sequence is selected from aa 344-356 of Mouse Cckar

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Small volumes of Cckar blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).

48,437 Da

cholecystokinin A receptor

cholecystokinin receptor type A

Cholecystokinin receptor type A

CCK-A receptor; CCK-AR; CCK1-R??[Similar Products]

CCKAR_MOUSE

CCKAR: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: cytoplasm; endoplasmic reticulum; endosome; lysosome; plasma membrane; terminal button

Molecular Function: cholecystokinin receptor activity

Biological Process: actin cytoskeleton reorganization; axonogenesis; digestion; eating behavior; elevation of cytosolic calcium ion concentration; feeding behavior; forebrain development; gastric acid secretion; insulin secretion; neuron migration; pancreatic juice secretion; reduction of food intake in response to dietary excess; regulation of calcium ion transport; regulation of hormone secretion; regulation of potassium ion transport; response to heat; response to starvation; thermoregulation

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