Product Name
Glucosylceramidase (GBA), Recombinant Protein
Full Product Name
Recombinant Bovine Glucosylceramidase (GBA)
Product Gene Name
GBA recombinant protein
[Similar Products]
Product Synonym Gene Name
GBA[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
40-536aa, Full Length of Mature Protein
Sequence
ARPCSPKSFG YSSVVCVCNG TYCDSLDPLT LPDPGTFSRF ESTRSGRRME LSLGTIQANR TGTGLLLTLQ PDQKFQKVKG FGGAMTDAAA LNILALSPAA RNLLLKSYFS EEGIEYNIIR VPMASCDFSI RTYTYDDSPD DFQLLNFSLP EEDVKLKIPL IHQALELANR SVSLFASPWT SPTWLKTNGA VNGKGTLKGQ AGDLYHKTWA RYFVKFLDAY AEHKLRFWAV TAENEPTAGL LTGYPFQCLG FTPEHQRDFI ARDLGPILAN STHRDVRLLM LDDQRLLLPR WAQVVLADPE AAKYVHGIAV HWYLDFLAPA KATLGETHRL FPNTMLFASE ACVGSKFWEQ SVRLGSWDRG MRYSHSIITN LLYHVVGWTD WNLALNPEGG PNWVRNFVDS PIIVDIAKDT FYKQPMFYHL GHFSKFIPEG SQRVGLVASK KSDLDTVALL RPDGSAVAVV LNRSSKDVPL TIKDPAVGFM ETVSPGYSIH TYLWRRQ
3D Structure
ModBase 3D Structure for Q2KHZ8
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of GBA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
GBA recombinant protein
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein.
NCBI/Uniprot data below describe general gene information for GBA. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001039886.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001046421.2
[Other Products]
UniProt Primary Accession #
Q2KHZ8
[Other Products]
UniProt Related Accession #
Q2KHZ8[Other Products]
Molecular Weight
59,855 Da
NCBI Official Full Name
glucosylceramidase
NCBI Official Synonym Full Names
glucosylceramidase beta
NCBI Official Symbol
GBA??[Similar Products]
NCBI Protein Information
glucosylceramidase
UniProt Protein Name
Glucosylceramidase
UniProt Synonym Protein Names
Acid beta-glucosidase; Beta-glucocerebrosidase; D-glucosyl-N-acylsphingosine glucohydrolase
Protein Family
Glucosylceramidase
UniProt Gene Name
GBA??[Similar Products]
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
