Product Name
MTAP, Blocking Peptide
Full Product Name
MTAP Peptide - N-terminal region
Product Gene Name
MTAP blocking peptide
[Similar Products]
MTAP peptide (MBS3234043) is used for blocking the activity of MTAP antibody (MBS3209080)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
Synthetic peptide located within the following region: ASGTTTTAVK IGIIGGTGLD DPEILEGRTE KYVDTPFGKP SDALILGKIK
3D Structure
ModBase 3D Structure for Q13126
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of MTAP blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
MTAP blocking peptide
This is a synthetic peptide designed for use in combination with anti-MTAP Antibody, made
Target Description: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.
Product Categories/Family for MTAP blocking peptide
Peptide
Applications Tested/Suitable for MTAP blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for MTAP. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002442
[Other Products]
NCBI GenBank Nucleotide #
NM_002451.4
[Other Products]
UniProt Primary Accession #
Q13126
[Other Products]
UniProt Related Accession #
Q13126[Other Products]
NCBI Official Full Name
S-methyl-5'-thioadenosine phosphorylase
NCBI Official Synonym Full Names
methylthioadenosine phosphorylase
NCBI Official Symbol
MTAP??[Similar Products]
NCBI Official Synonym Symbols
BDMF; MSAP; DMSFH; LGMBF; DMSMFH; c86fus; HEL-249
??[Similar Products]
NCBI Protein Information
S-methyl-5'-thioadenosine phosphorylase
UniProt Protein Name
S-methyl-5'-thioadenosine phosphorylase
UniProt Synonym Protein Names
5'-methylthioadenosine phosphorylase
UniProt Gene Name
MTAP??[Similar Products]
UniProt Entry Name
MTAP_HUMAN
NCBI Summary for MTAP
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq, Jul 2008]
Research Articles on MTAP
1. melanoma risk alleles correlate with an allele-specific hyper-methylation and down-regulation of gene expression
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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