Product Name
Paired Box Gene 9 (PAX9), Polyclonal Antibody
Full Product Name
Biotin-Linked Polyclonal Antibody to Paired Box Gene 9 (PAX9)
Product Gene Name
anti-PAX9 antibody
[Similar Products]
Matching Pairs
Unconjugated Antibody: Paired Box Gene 9 (MBS2032427)
Biotin Conjugated Antibody: Paired Box Gene 9 (PAX9) (MBS2096424)
Matching Pairs
Biotin Conjugated Antibody: Paired Box Gene 9 (PAX9) (MBS2096424)
Immunogen: Paired Box Gene 9 (MBS2033404)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Concentration
200ug/ml (lot specific)
Immunogen
PAX9 (Met1~Leu341)
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customera??s specifications, please inquire.
Other Notes
Small volumes of anti-PAX9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-PAX9 antibody
Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for PAX9. It may not necessarily be applicable to this product.
NCBI Accession #
EAW65853.1
[Other Products]
UniProt Secondary Accession #
Q99582; Q9UQR4[Other Products]
UniProt Related Accession #
P55771[Other Products]
Molecular Weight
36,310 Da
NCBI Official Full Name
paired box gene 9
NCBI Official Synonym Full Names
paired box 9
NCBI Official Symbol
PAX9??[Similar Products]
NCBI Official Synonym Symbols
STHAG3
??[Similar Products]
NCBI Protein Information
paired box protein Pax-9
UniProt Protein Name
Paired box protein Pax-9
Protein Family
Paired box protein
UniProt Gene Name
PAX9??[Similar Products]
NCBI Summary for PAX9
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. Mice lacking this gene exhibit impaired development of organs, musculature and the skeleton, including absent and abnormally developed teeth, and neonatal lethality. Mutations in the human gene are associated with selective tooth agenesis-3. [provided by RefSeq, Sep 2015]
UniProt Comments for PAX9
PAX9: Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs. Interacts with KDM5B.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 14q13.3
Cellular Component: nucleus
Molecular Function: protein binding
Biological Process: endoderm development; negative regulation of transcription, DNA-dependent; odontogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of odontogenesis; transcription from RNA polymerase II promoter
Disease: Tooth Agenesis, Selective, 3
Research Articles on PAX9
1. in vitro functional analysis creating PAX9 minigene construct did apparently show no effect on the splice-site migration. It is therefore proposed that haploinsufficiency of PAX9 is the causal factor for tooth agenesis in this family.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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