Product Name
Paired Box 9 (PAX9), Recombinant Protein
Full Product Name
Recombinant Human Paired Box 9
Product Synonym Names
PAX9 Human; Paired Box 9 Human Recombinant; Paired Box 9; STHAG3; Paired Box Gene 9; Paired Box Protein Pax-9; Paired Domain Gene 9
Product Gene Name
PAX9 recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMEP AFGE VNQLGGVFVN GRPLPNAIRL RIVELAQLGI RPCDISRQLR VSHGCVSKIL ARYNETGSIL PGAIGGSKPR VTTPTVVKHI RTYKQRDPGI FAWEIRDRLL ADGVCDKYNV PSVSSISRIL RNKIGNLAQQ GHYDSYKQHQ PTPQPALPYN HIYSYPSPIT AAAAKVPTPP GVPAIPGSVA MPRTWPSSHS VTDILGIRSI TDQVSDSSPY HSPKVEEWSS LGRNNFPAAA PHAVNGLEKG ALEQEAKYGQ APNGLPAVGS FVSASSMAPY PTPAQVSPYM TYSAAPSGYV AGHGWQHAGG TSLSPHNCDI PASLAFKGMQ AAREGSHSVT ASAL.
3D Structure
ModBase 3D Structure for P55771
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Form/Format
PAX9 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Sterile Filtered clear solution.
Other Notes
Small volumes of PAX9 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
PAX9 recombinant protein
Description: PAX9 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 364 amino acids (1-341 a.a) and having a molecular mass of 38.7kDa.PAX9 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: PAX9 (Paired box protein Pax-9) belongs to the paired box (PAX) family of transcription factors. Members of PAX9 family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. In addition, PAX9 is vital for the development of different organs and skeletal elements.
Product Categories/Family for PAX9 recombinant protein
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins
NCBI/Uniprot data below describe general gene information for PAX9. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006185.1
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NCBI GenBank Nucleotide #
NM_006194.3
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UniProt Primary Accession #
P55771
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UniProt Secondary Accession #
Q99582; Q9UQR4[Other Products]
UniProt Related Accession #
P55771[Other Products]
Molecular Weight
36,310 Da
NCBI Official Full Name
paired box protein Pax-9
NCBI Official Synonym Full Names
paired box 9
NCBI Official Symbol
PAX9??[Similar Products]
NCBI Official Synonym Symbols
STHAG3
??[Similar Products]
NCBI Protein Information
paired box protein Pax-9; paired domain gene 9
UniProt Protein Name
Paired box protein Pax-9
Protein Family
Paired box protein
UniProt Gene Name
PAX9??[Similar Products]
UniProt Entry Name
PAX9_HUMAN
NCBI Summary for PAX9
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 9 gene is unknown but it may involve development of stratified squamous epithelia as well as various organs and skeletal elements. [provided by RefSeq, Jul 2008]
UniProt Comments for PAX9
PAX9: Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs. Interacts with KDM5B.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 14q13.3
Cellular Component: nucleus
Molecular Function: protein binding
Biological Process: odontogenesis; transcription, DNA-dependent; regulation of odontogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; endoderm development
Disease: Tooth Agenesis, Selective, 3
Research Articles on PAX9
1. Probably other genes can determine phenotypical patterns of dental agenesis in the families studied, different than the ones described in the mutations of PAX9
Precautions
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Disclaimer
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