For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

The antibody is a rabbit polyclonal antibody raised against CHAF1B. It has beenselected for its ability to recognize CHAF1B in immunohistochemical staining andwestern blotting.

Affinity Chromatography

Liquid

200ug/ml (lot specific)

Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customera??s specifications, please inquire.

Small volumes of anti-CHAF1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)

Western blotting: 0.2-2ug/mL;1:250-2500
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.

Western Blot: Sample: Recombinant protein.

DABstainingonIHC-P.Samples:MouseTissue)

63,132 Da

chromatin assembly factor 1, subunit B (p60)

chromatin assembly factor 1 subunit B

Chromatin assembly factor 1 subunit B

CAF-1 subunit B; CAF-I 60 kDa subunit; CAF-I p60??[Similar Products]

CAF-1B: Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. The CCR4-NOT complex functions as general transcription regulation complex. Belongs to the WD repeat HIR1 family.

Protein type: DNA replication

Chromosomal Location of Human Ortholog: 16 C4|16 54.96 cM

Cellular Component: cytosol; nuclear chromatin; nucleoplasm; nucleus; protein complex

Molecular Function: histone binding; protein binding

Biological Process: cell cycle; cellular response to DNA damage stimulus; chromatin assembly; DNA repair; DNA replication; DNA replication-dependent nucleosome assembly; nucleosome assembly; regulation of transcription, DNA-templated; transcription, DNA-dependent

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