Full Product Name
Mouse monoclonal MSX1 antibody
Product Synonym Names
MSX1 antibody
Product Gene Name
anti-MSX1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Form/Format
Supplied as ascitic fluid containing 0.03% sodium azide
Concentration
1 mg/ml (lot specific)
Immunogen
MSX1 antibody was raised in Rabbit using a purified recombinant fragment of human MSX1 expressed in E Coli as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage, store at -20 degree C.
Other Notes
Small volumes of anti-MSX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-MSX1 antibody
DNA & RNA
Applications Tested/Suitable for anti-MSX1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-MSX1 antibody
WB: 1:500-1:2000
ELISA: 1-10000
Western Blot (WB) of anti-MSX1 antibody
Figure 1: Western blot analysis using MSX1 mouse mAb against NTERA-2 cell lysate.
NCBI/Uniprot data below describe general gene information for MSX1. It may not necessarily be applicable to this product.
NCBI Accession #
AAH67353.1
[Other Products]
UniProt Secondary Accession #
Q96NY4; A0SZU5; A8K3M1[Other Products]
UniProt Related Accession #
P28360[Other Products]
Molecular Weight
31,496 Da
NCBI Official Full Name
MSX1 protein
NCBI Official Synonym Full Names
msh homeobox 1
NCBI Official Symbol
MSX1??[Similar Products]
NCBI Official Synonym Symbols
HOX7; HYD1; ECTD3; STHAG1
??[Similar Products]
NCBI Protein Information
homeobox protein MSX-1
UniProt Protein Name
Homeobox protein MSX-1
UniProt Synonym Protein Names
Homeobox protein Hox-7; Msh homeobox 1-like protein
Protein Family
Homeobox protein
UniProt Gene Name
MSX1??[Similar Products]
UniProt Synonym Gene Names
HOX7??[Similar Products]
NCBI Summary for MSX1
This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia. [provided by RefSeq, Jul 2008]
UniProt Comments for MSX1
MSX1: Acts as a transcriptional repressor. May play a role in limb-pattern formation. Acts in cranofacial development and specifically in odontogenesis. Expression in the developing nail bed mesenchyme is important for nail plate thickness and integrity. Expressed in the developing nail bed mesenchyme. Belongs to the Msh homeobox family.
Protein type: DNA-binding; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 4p16.2
Cellular Component: cytoplasm; nucleoplasm; nucleus
Molecular Function: p53 binding
Biological Process: cell morphogenesis; negative regulation of cell growth; odontogenesis of dentine-containing teeth; positive regulation of DNA damage response, signal transduction by p53 class mediator; protein stabilization
Disease: Orofacial Cleft 5; Tooth Agenesis, Selective, 1; Witkop Syndrome
Research Articles on MSX1
1. T variation in the MSX1 gene. This variant in the 3' untranslated region is located 6 bp downstream of the stop codon (TAG) in exon 2. We revealed a statistically significant association between the MSX1 c.*6C > T variant and Nonsyndromic cleft lip/palate in Turkey ( p = 0.01).">We found the c.*6C > T variation in the MSX1 gene. This variant in the 3' untranslated region is located 6 bp downstream of the stop codon (TAG) in exon 2. We revealed a statistically significant association between the MSX1 c.*6C > T variant and Nonsyndromic cleft lip/palate in Turkey ( p = 0.01).
Precautions
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Disclaimer
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