HOX7; HYD1; STHAG1; MSX1

For Research Use Only. Not for use in diagnostic procedures.

IgG1

5D11

Mouse

Ascitic fluid containing 0.03% sodium azide.

Store at 4 degree C, for long term storage, store at-20 degree C.

Small volumes of anti-MSX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Drosophila, muscle segment (msh) homolog 1, homeo domain encoding gene, inhibiting MYOD1 expression, highly expressed in dental mesenchyme during critical bud stage, involved in epithelial-mesenchymal signaling in many organs, and in the pathogenesis of cleft lip and palate, interacting with MSX2 in mouse limb bud patterning. This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition.Tissue specificity: Expressed in the developing nail bed mesenchyme.

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

Western Blot (WB), ELISA (EIA)

WB: 1:500-1:2000
ELISA: 1:10000

Figure 1: Western blot analysis using MSX1 mouse mAb against NTERA-2 cell lysate.

31kDa

msh homeobox 1

homeobox protein MSX-1

Homeobox protein MSX-1

HOX7??[Similar Products]

This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia. [provided by RefSeq, Jul 2008]

Acts as a transcriptional repressor. May play a role in limb-pattern formation. Acts in cranofacial development and specifically in odontogenesis. Expression in the developing nail bed mesenchyme is important for nail plate thickness and integrity.

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