Full Product Name
UPB1 Polyclonal Antibody
Product Synonym Names
AI195023; Beta alanine synthase; Beta ureidopropionase; BUP1; N carbamoyl beta alanine amidohydrolase; Ureidopropionase; beta
Product Gene Name
anti-UPB1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9UBR1
Species Reactivity
Mouse, Rat
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration
1 mg/mL (lot specific)
Immunogen
Recombinant protein of human UPB1
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-UPB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-UPB1 antibody
This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.
Product Categories/Family for anti-UPB1 antibody
Epigenetics and Nuclear Signaling; Metabolism; Signal Transduction
Applications Tested/Suitable for anti-UPB1 antibody
Western Blot (WB)
Application Notes for anti-UPB1 antibody
WB: 1:200-1:2000
Western Blot (WB) of anti-UPB1 antibody
Western blot analysis of extracts of various cell lines, using UPB1 antibody.
NCBI/Uniprot data below describe general gene information for UPB1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_057411.1
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NCBI GenBank Nucleotide #
NM_016327.2
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UniProt Primary Accession #
Q9UBR1
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UniProt Secondary Accession #
Q9UIR3; A3KMF8[Other Products]
UniProt Related Accession #
Q9UBR1[Other Products]
Molecular Weight
Calculated: 43kDa
Observed: 43kDa
NCBI Official Full Name
beta-ureidopropionase
NCBI Official Synonym Full Names
beta-ureidopropionase 1
NCBI Official Symbol
UPB1??[Similar Products]
NCBI Official Synonym Symbols
BUP1
??[Similar Products]
NCBI Protein Information
beta-ureidopropionase
UniProt Protein Name
Beta-ureidopropionase
UniProt Synonym Protein Names
BUP-1; Beta-alanine synthase; N-carbamoyl-beta-alanine amidohydrolase
Protein Family
Transcription factor
UniProt Gene Name
UPB1??[Similar Products]
UniProt Synonym Gene Names
BUP1??[Similar Products]
NCBI Summary for UPB1
This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq, Jul 2008]
UniProt Comments for UPB1
Converts N-carbamoyl-beta-aminoisobutyrate and N-carbamoyl-beta-alanine (3-ureidopropanoate) to, respectively, beta-aminoisobutyrate and beta-alanine, ammonia and carbon dioxide.
Research Articles on UPB1
1. A (p.R326Q) is the most common mutation of the UPB1 gene in Chinese. The predicted incidence indicates that beta-ureidopropionase deficiency is significantly underdiagnosed in the Chinese population.">The c.977G>A (p.R326Q) is the most common mutation of the UPB1 gene in Chinese. The predicted incidence indicates that beta-ureidopropionase deficiency is significantly underdiagnosed in the Chinese population.
Precautions
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Disclaimer
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