Human V-type proton ATPase subunit C 2 (ATP6V1C2) ELISA kit; ATP6C2; VMA5; V-ATPase C2 subunit; vacuolar H+ ATPase C2; ATPase; H+ transporting; lysosomal 42kDa; V1 subunit C2

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of ATP6V1C2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9318311 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 (ATP6V1C2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ATP6V1C2. The ELISA analytical biochemical technique of the MBS9318311 kit is based on ATP6V1C2 antibody-ATP6V1C2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ATP6V1C2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ATP6V1C2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

48,759 Da

ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2

V-type proton ATPase subunit C 2; V-ATPase C2 subunit; V-ATPase subunit C 2; vacuolar proton pump subunit C 2

V-type proton ATPase subunit C 2

V-ATPase subunit C 2??[Similar Products]

VATC2_HUMAN

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms. [provided by RefSeq, Jul 2008]

ATP6V1C2: Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Belongs to the V-ATPase C subunit family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Energy Metabolism - oxidative phosphorylation; EC 3.6.3.14; Hydrolase

Chromosomal Location of Human Ortholog: -

Cellular Component: lysosomal membrane; cytosol

Molecular Function: hydrogen-exporting ATPase activity, phosphorylative mechanism; protein dimerization activity

Biological Process: interaction with host; cellular iron ion homeostasis; ATP hydrolysis coupled proton transport; insulin receptor signaling pathway; transferrin transport; positive regulation of Wnt receptor signaling pathway; transmembrane transport

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