Product Name
PTPN14, Blocking Peptide
Full Product Name
PTPN14 Peptide - middle region
Product Gene Name
PTPN14 blocking peptide
[Similar Products]
Product Synonym Gene Name
PEZ; PTP36[Similar Products]
PTPN14 peptide (MBS3246625) is used for blocking the activity of PTPN14 antibody (MBS3221907)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
Synthetic peptide located within the following region: PQGVYSNKLV SPSDQRNPKN NVVPSKPGAS AISHTVSTPE LANMQLQGSH
3D Structure
ModBase 3D Structure for Q15678
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of PTPN14 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
PTPN14 blocking peptide
This is a synthetic peptide designed for use in combination with anti- PTPN14 Antibody, made
Target Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia.
Product Categories/Family for PTPN14 blocking peptide
Peptide
NCBI/Uniprot data below describe general gene information for PTPN14. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005392.2
[Other Products]
NCBI GenBank Nucleotide #
NM_005401.4
[Other Products]
UniProt Primary Accession #
Q15678
[Other Products]
UniProt Related Accession #
Q15678[Other Products]
NCBI Official Full Name
tyrosine-protein phosphatase non-receptor type 14
NCBI Official Synonym Full Names
protein tyrosine phosphatase non-receptor type 14
NCBI Official Symbol
PTPN14??[Similar Products]
NCBI Official Synonym Symbols
PEZ; PTP36; CATLPH
??[Similar Products]
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type 14
UniProt Protein Name
Tyrosine-protein phosphatase non-receptor type 14
UniProt Synonym Protein Names
Protein-tyrosine phosphatase pez
Protein Family
Tyrosine-protein phosphatase non-receptor
UniProt Gene Name
PTPN14??[Similar Products]
UniProt Synonym Gene Names
PEZ; PTPD2??[Similar Products]
UniProt Entry Name
PTN14_HUMAN
NCBI Summary for PTPN14
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia. [provided by RefSeq, Sep 2010]
Research Articles on PTPN14
1. p53 deficiency promotes Yap signaling and that PTPN14 and TP53 mutations are mutually exclusive in human cancers.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
