Full Product Name
UTP4 Antibody - middle region
Product Gene Name
anti-UTP4 antibody
[Similar Products]
Product Synonym Gene Name
NAIC; CIRH1A; CIRHIN; TEX292[Similar Products]
Antibody/Peptide Pairs
UTP4 peptide (MBS3239827) is used for blocking the activity of UTP4 antibody (MBS3214900)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: ADVQSIAVAD QEDSFVVGTA EGTVFHFQLV PVTSNSSEKQ WVRTKPFQHH
3D Structure
ModBase 3D Structure for Q969X6
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 79%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human CIRH1A
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-UTP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-UTP4 antibody
This is a rabbit polyclonal antibody against CIRH1A. It was validated on Western Blot
Target Description: This gene encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence. Alternative splicing results in multiple transcript variants.
Product Categories/Family for anti-UTP4 antibody
Polyclonal; Disease Related;
Applications Tested/Suitable for anti-UTP4 antibody
Western Blot (WB)
Western Blot (WB) of anti-UTP4 antibody
Host: Rabbit
Target Name: CIRH1A
Sample Type: 721_B Whole Cell lysates
Antibody Dilution: 1.0ug/ml
NCBI/Uniprot data below describe general gene information for UTP4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_116219.2
[Other Products]
NCBI GenBank Nucleotide #
NM_032830.3
[Other Products]
UniProt Primary Accession #
Q969X6
[Other Products]
UniProt Related Accession #
Q969X6[Other Products]
NCBI Official Full Name
U3 small nucleolar RNA-associated protein 4 homolog isoform 1
NCBI Official Synonym Full Names
UTP4 small subunit processome component
NCBI Official Symbol
UTP4??[Similar Products]
NCBI Official Synonym Symbols
NAIC; CIRH1A; CIRHIN; TEX292
??[Similar Products]
NCBI Protein Information
U3 small nucleolar RNA-associated protein 4 homolog
UniProt Protein Name
Cirhin
Protein Family
U3 small nucleolar RNA-associated protein
UniProt Gene Name
CIRH1A??[Similar Products]
UniProt Synonym Gene Names
KIAA1988; UTP4??[Similar Products]
UniProt Entry Name
CIR1A_HUMAN
NCBI Summary for UTP4
This gene encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Research Articles on UTP4
1. Results show that CIRH1A was highly expressed in carcinoma samples and colorectal cancer cells and suggest that CIRH1A plays a critical role in the proliferation, cell cycle distribution, and apoptosis of human malignant colorectal cells.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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