Product Name
ARHGAP26, cDNA Clone
Full Product Name
ARHGAP26 cDNA Clone
Product Gene Name
ARHGAP26 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggggctcc cagcgctcga gttcagcgac tgctgcctcg atagtccgca cttccgagag acgctcaagt cgcacgaagc agagctggac aagaccaaca aattcatcaa ggagctcatc aaggacggga agtcactcat aagcgcgctc aagaatttgt cttcagcgaa gcggaagttt gcagattcct taaatgaatt taaatttcag tgcataggag atgcagaaac agatgatgag atgtgtatag caaggtcttt gcaggagttt gccactgtcc tcaggaatct tgaagatgaa cggatacgga tgattgagaa tgccagcgag gtgctcatca ctcccttgga gaagtttcga aaggaacaga tcggggctgc caaggaagcc aaaaagaagt atgacaaaga gacagaaaag tattgtggca tcttagaaaa acacttgaat ttgtcttcca aaaagaaaga atctcagctt caggaggcag acagccaagt ggacctggtc cggcagcatt tctatgaagt atccctggaa tatgtcttca aggtgcagga agtccaagag agaaagatgt ttgagtttgt ggagcctctg ctggccttcc tgcaaggact cttcactttc tatcaccatg gttacgaact ggccaaggat ttcggggact tcaagacaca gttaaccatt agcatacaga acacaagaaa tcgctttgaa ggcactagat cagaagtgga atcactgatg aaaaagatga aggagaatcc ccttgagcac aagaccatca gtccctacac catggaggga tacctctacg tgcaggagaa acgtcacttt ggaacttctt gggtgaagca ctactgtaca tatcaacggg attccaaaca aatcaccatg gtaccatttg accaaaagtc aggaggaaaa gggggagaag atgaatcagt tatcctcaaa tcctgcacac ggcggaaaac agactccatt gagaagaggt tttgctttga tgtggaagca gtagacaggc caggggttat caccatgcaa gctttgtcgg aagaggaccg gaggctctgg atggaagcca tggatggccg ggaacctgtc tacaactcga acaaagacag ccagagtgaa gggactgcgc agttggacag cattggcttc agcataatca ggaaatgcat ccatgctgtg gaaaccagag ggatcaacga gcaagggctg tatcgaattg tgggggtcaa ctccagagtg cagaagttgc tgagtgtcct gatggacccc aagactgctt ctgagacaga aacagatatc tgtgctgaat gggagataaa gaccatcact agtgctctga agacctacct aagaatgctt ccaggaccac tcatgatgta ccagtttcaa agaagtttca tcaaagcagc aaaactggag aaccaggagt ctcgggtctc tgaaatccac agccttgttc atcggctccc agagaaaaat cggcagatgt tacagctgct catgaaccac ttggcaaatg ttgctaacaa ccacaagcag aatttgatga cggtggcaaa ccttggtgtg gtgtttggac ccactctgct gaggcctcag gaagaaacag tagcagccat catggacatc aaatttcaga acattgtcat tgagatccta atagaaaacc acgaaaagat atttaacacc gtgcccgata tgcctctcac caatgcccag ctgcacctgt ctcggaagaa gagcagtgac tccaagcccc cgtcctgcag cgagaggccc ctgacgctct tccacaccgt tcagtcaaca gagaaacagg aacaaaggaa cagcatcatc aactccagtt tggaatctgt ctcatcaaat ccaaacagca tccttaattc cagcagcagc ttacagccca acatgaactc cagtgaccca gacctggctg tggtcaaacc cacccggccc aactcactcc ccccgaatcc aagcccaact tcacccctct cgccatcttg gcccatgttc tcggcgccat ccagccctat gcccacctca tccacgtcca gcgactcatc ccccgtcagc acaccgttcc ggaaggcaaa agccttgtat gcctgcaaag ctgaacatga ctcagaactt tcgttcacag caggcacggt cttcgataat gttcacccat ctcaggagcc tggctggttg gaggggactc tgaacggaaa gactggcctc atccctgaga attacgtgga gttcctctaa
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ARHGAP26 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ARHGAP26. It may not necessarily be applicable to this product.
NCBI Accession #
BC068555
[Other Products]
UniProt Secondary Accession #
O75117; Q5D035; Q9BYS6; Q9BYS7; Q9UJ00[Other Products]
UniProt Related Accession #
Q9UNA1[Other Products]
Molecular Weight
86,165 Da
NCBI Official Full Name
Homo sapiens Rho GTPase activating protein 26, mRNA
NCBI Official Synonym Full Names
Rho GTPase activating protein 26
NCBI Official Symbol
ARHGAP26??[Similar Products]
NCBI Official Synonym Symbols
GRAF; GRAF1; OPHN1L; OPHN1L1
??[Similar Products]
NCBI Protein Information
rho GTPase-activating protein 26
UniProt Protein Name
Rho GTPase-activating protein 26
UniProt Synonym Protein Names
GTPase regulator associated with focal adhesion kinase; Oligophrenin-1-like protein; Rho-type GTPase-activating protein 26
Protein Family
Rho GTPase-activating protein
UniProt Gene Name
ARHGAP26??[Similar Products]
UniProt Synonym Gene Names
GRAF; KIAA0621; OPHN1L??[Similar Products]
UniProt Entry Name
RHG26_HUMAN
NCBI Summary for ARHGAP26
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
UniProt Comments for ARHGAP26
ARHGAP26: GTPase-activating protein for RHOA and CDC42. Interacts with NYAP1, NYAP2 and MYO16. Binds to the C-terminus of PTK2/FAK1. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Oncoprotein; GAPs; Motility/polarity/chemotaxis; GAPs, Rac/Rho
Chromosomal Location of Human Ortholog: 5q31
Cellular Component: cytosol
Molecular Function: GTPase activator activity; phospholipid binding; protein binding
Biological Process: regulation of small GTPase mediated signal transduction
Disease: Juvenile Myelomonocytic Leukemia
Research Articles on ARHGAP26
1. GRAF expression is a favorable prognostic marker in patients with acute myeloid leukemia.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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