Product Name
ARHGAP26, Polyclonal Antibody
Full Product Name
ARHGAP26 Antibody
Product Gene Name
anti-ARHGAP26 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human
Predicted: Mouse, Rat
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3.
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Other Notes
Small volumes of anti-ARHGAP26 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ARHGAP26 antibody
Rabbit polyclonal ARHGAP26 (1) antibody was raised against a recombinated human ARHGAP26 protein 377-550aa (BC068555).
Product Categories/Family for anti-ARHGAP26 antibody
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
Applications Tested/Suitable for anti-ARHGAP26 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ARHGAP26 antibody
ELISA: 1:20,000-1:80,000
WB: 1:1,000-1:2,000
IHC: 1:100-1:500
Testing Data of anti-ARHGAP26 antibody
Testing Data of anti-ARHGAP26 antibody
NCBI/Uniprot data below describe general gene information for ARHGAP26. It may not necessarily be applicable to this product.
NCBI Accession #
BC068555
[Other Products]
UniProt Secondary Accession #
O75117; Q5D035; Q9BYS6; Q9BYS7; Q9UJ00[Other Products]
UniProt Related Accession #
Q9UNA1[Other Products]
Molecular Weight
86,165 Da
NCBI Official Full Name
Homo sapiens Rho GTPase activating protein 26, mRNA
NCBI Official Synonym Full Names
Rho GTPase activating protein 26
NCBI Official Symbol
ARHGAP26??[Similar Products]
NCBI Official Synonym Symbols
GRAF; GRAF1; OPHN1L; OPHN1L1
??[Similar Products]
NCBI Protein Information
rho GTPase-activating protein 26
UniProt Protein Name
Rho GTPase-activating protein 26
UniProt Synonym Protein Names
GTPase regulator associated with focal adhesion kinase; Oligophrenin-1-like protein; Rho-type GTPase-activating protein 26
Protein Family
Rho GTPase-activating protein
UniProt Gene Name
ARHGAP26??[Similar Products]
UniProt Synonym Gene Names
GRAF; KIAA0621; OPHN1L??[Similar Products]
NCBI Summary for ARHGAP26
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
UniProt Comments for ARHGAP26
GTPase-activating protein for RHOA and CDC42.
Product References and Citations for anti-ARHGAP26 antibody
(1) Doherty, G.J., Ahlund, M.K., Howes, M.T., et al. The endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading. Mol. Biol. Cell 22 (22), 4380-4389 (2011).
Research Articles on ARHGAP26
1. We conclude that a transient interaction between Cdc42 and GRAF1 drives endocytic turnover and controls the transition essential for endosomal maturation of plasma membrane internalised by this mechanism.
Precautions
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Disclaimer
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