Product Name
ARHGAP26, Polyclonal Antibody
Full Product Name
ARHGAP26 Antibody - middle region
Product Gene Name
anti-ARHGAP26 antibody
[Similar Products]
Product Synonym Gene Name
GRAF; GRAF1; OPHN1L; OPHN1L1[Similar Products]
Antibody/Peptide Pairs
ARHGAP26 peptide (MBS3244348) is used for blocking the activity of ARHGAP26 antibody (MBS3219469)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: LWMEAMDGRE PVYNSNKDSQ SEGTAQLDSI GFSIIRKCIH AVETRGINEQ
3D Structure
ModBase 3D Structure for Q9UNA1
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human RHG26
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ARHGAP26 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ARHGAP26 antibody
This is a rabbit polyclonal antibody against RHG26. It was validated on Western Blot
Target Description: Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-ARHGAP26 antibody
Cancer; Signaling Intermediate; Cell Adhesion; Signal Transduction; Disease Related;
Applications Tested/Suitable for anti-ARHGAP26 antibody
Western Blot (WB)
Western Blot (WB) of anti-ARHGAP26 antibody
Host: Rabbit
Target Name: RHG26
Sample Type: 721_B Whole Cell lysates
Antibody Dilution: 1.0ug/ml
NCBI/Uniprot data below describe general gene information for ARHGAP26. It may not necessarily be applicable to this product.
NCBI Accession #
NP_055886
[Other Products]
NCBI GenBank Nucleotide #
NM_015071.6
[Other Products]
UniProt Primary Accession #
Q9UNA1
[Other Products]
UniProt Related Accession #
Q9UNA1[Other Products]
NCBI Official Full Name
rho GTPase-activating protein 26 isoform a
NCBI Official Synonym Full Names
Rho GTPase activating protein 26
NCBI Official Symbol
ARHGAP26??[Similar Products]
NCBI Official Synonym Symbols
GRAF; GRAF1; OPHN1L; OPHN1L1
??[Similar Products]
NCBI Protein Information
rho GTPase-activating protein 26
UniProt Protein Name
Rho GTPase-activating protein 26
UniProt Synonym Protein Names
GTPase regulator associated with focal adhesion kinase; Oligophrenin-1-like protein; Rho-type GTPase-activating protein 26
Protein Family
Rho GTPase-activating protein
UniProt Gene Name
ARHGAP26??[Similar Products]
UniProt Synonym Gene Names
GRAF; KIAA0621; OPHN1L??[Similar Products]
UniProt Entry Name
RHG26_HUMAN
NCBI Summary for ARHGAP26
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
Research Articles on ARHGAP26
1. GRAF1 plays a role in the maintenance of normal epithelial phenotype and its depletion leads to an epithelial-mesenchymal transition-like process that might be involved in neoplastic transformation.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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