Product Name
SH3BP2, Blocking Peptide
Full Product Name
SH3BP2 Peptide - middle region
Product Gene Name
SH3BP2 blocking peptide
[Similar Products]
Product Synonym Gene Name
3BP2; CRBM; CRPM; FLJ42079; RES4-23; 3BP-2[Similar Products]
SH3BP2 peptide (MBS3237789) is used for blocking the activity of SH3BP2 antibody (MBS3212843)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P78314
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of SH3BP2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
SH3BP2 blocking peptide
This is a synthetic peptide designed for use in combination with anti-SH3BP2 antibody made
Target Description: SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism.
Product Categories/Family for SH3BP2 blocking peptide
Peptide
Applications Tested/Suitable for SH3BP2 blocking peptide
Immunohistochemistry (IHC), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for SH3BP2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_003014
[Other Products]
NCBI GenBank Nucleotide #
NM_003023
[Other Products]
UniProt Primary Accession #
P78314
[Other Products]
UniProt Related Accession #
P78314[Other Products]
NCBI Official Full Name
SH3 domain-binding protein 2 isoform a
NCBI Official Synonym Full Names
SH3 domain binding protein 2
NCBI Official Symbol
SH3BP2??[Similar Products]
NCBI Official Synonym Symbols
3BP2; CRBM; CRPM; 3BP-2; RES4-23
??[Similar Products]
NCBI Protein Information
SH3 domain-binding protein 2
UniProt Protein Name
SH3 domain-binding protein 2
Protein Family
SH3 domain-binding protein
UniProt Gene Name
SH3BP2??[Similar Products]
UniProt Synonym Gene Names
3BP2; 3BP-2??[Similar Products]
UniProt Entry Name
3BP2_HUMAN
NCBI Summary for SH3BP2
The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Research Articles on SH3BP2
1. C; p.Arg415Pro SH3BP2 mutation">All members featured a heterozygous missense c.1244G>C; p.Arg415Pro SH3BP2 mutation
Precautions
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Disclaimer
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