For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

Affinity Purified

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Small volumes of anti-SH3BP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

This is a rabbit polyclonal antibody against SH3BP2. It was validated on Western Blot using a cell lysate as a positive control.

Target Description: SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism.

Polyclonal; Signal Proteins; Lymphocyte Signaling; Membrane Protein; Developmental Biology; Immunohistochemistry; Receptors;

Immunohistochemistry (IHC), Western Blot (WB)

Human Liver

Immunohistochemistry with Human kidney lysate tissue at an antibody concentration of 5.0ug/ml using anti-SH3BP2 antibody

WB Suggested Anti-SH3BP2 Antibody Titration: 1 ug/ml
Positive Control: 721_B cell lysateSH3BP2 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells

62kDa

SH3 domain binding protein 2

SH3 domain-binding protein 2

SH3 domain-binding protein 2

3BP2; 3BP-2??[Similar Products]

3BP2_HUMAN

The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

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