Product Name
glyceronephosphate O-acyltransferase (GNPAT), Polyclonal Antibody
Full Product Name
Rabbit anti-human glyceronephosphate O-acyltransferase polyclonal Antibody
Product Synonym Names
glyceronephosphate O-acyltransferase; GNPAT; DAP-AT; DAPAT; DHAPAT
Product Gene Name
anti-GNPAT antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-242920 / sc-242920
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-GNPAT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-GNPAT antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
NCBI/Uniprot data below describe general gene information for GNPAT. It may not necessarily be applicable to this product.
NCBI Accession #
AAH00450.1
[Other Products]
UniProt Secondary Accession #
Q5TBH7; Q9BWC2; B4DNM9[Other Products]
UniProt Related Accession #
O15228[Other Products]
Molecular Weight
69,906 Da[Similar Products]
NCBI Official Full Name
Glyceronephosphate O-acyltransferase
NCBI Official Synonym Full Names
glyceronephosphate O-acyltransferase
NCBI Official Symbol
GNPAT??[Similar Products]
NCBI Official Synonym Symbols
DAPAT; DAP-AT; DHAPAT
??[Similar Products]
NCBI Protein Information
dihydroxyacetone phosphate acyltransferase; DHAP-AT; glycerone-phosphate O-acyltransferase; acyl-CoA:dihydroxyacetonephosphateacyltransferase
UniProt Protein Name
Dihydroxyacetone phosphate acyltransferase
UniProt Synonym Protein Names
Acyl-CoA:dihydroxyacetonephosphateacyltransferase; Glycerone-phosphate O-acyltransferase
Protein Family
Dihydroxyacetone phosphate acyltransferase
UniProt Gene Name
GNPAT??[Similar Products]
UniProt Synonym Gene Names
DAPAT; DHAPAT; DAP-AT; DHAP-AT??[Similar Products]
UniProt Entry Name
GNPAT_HUMAN
NCBI Summary for GNPAT
This gene encodes an enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in this gene are associated with rhizomelic chondrodysplasia punctata. [provided by RefSeq, Jul 2008]
UniProt Comments for GNPAT
GNPAT: Defects in GNPAT are the cause of rhizomelic chondrodysplasia punctata type 2 (RCDP2). RDCP2 is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation. Belongs to the GPAT/DAPAT family.
Protein type: EC 2.3.1.42; Transferase; Lipid Metabolism - glycerophospholipid
Chromosomal Location of Human Ortholog: 1q42
Cellular Component: peroxisomal membrane; peroxisomal matrix; mitochondrion; membrane; peroxisome
Molecular Function: glycerone-phosphate O-acyltransferase activity; palmitoyl-CoA hydrolase activity; receptor binding
Biological Process: response to drug; response to starvation; synaptogenesis; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidic acid biosynthetic process; cerebellum morphogenesis; cellular lipid metabolic process; response to nutrient; paranodal junction assembly; ether lipid biosynthetic process
Disease: Rhizomelic Chondrodysplasia Punctata, Type 2
Research Articles on GNPAT
1. ACOX1 and GNPAT silencing up-regulated ceramide galactosyltransferase (UGT8) mRNA expression, and down-regulated UDP-glucoseceramide glucosyltransferase (UGCG).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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