Product Name
CUGBP Elav-like family member 6 (CELF6), Recombinant Protein
Full Product Name
Recombinant Human CUGBP Elav-like family member 6 (CELF6)
Product Gene Name
CELF6 recombinant protein
[Similar Products]
Product Synonym Gene Name
CELF6[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-481aa, full length protein
Sequence
MAAAPGGSAQ PAGPGPRLGF STADSGVGMS GLNPGPAVPM KDHDAIKLFV GQIPRGLDEQ DLKPLFEEFG RIYELTVLKD RLTGLHKGCA FLTYCARDSA LKAQSALHEQ KTLPGMNRPI QVKPAASEGR GEDRKLFVGM LGKQQGEEDV RRLFQPFGHI EECTVLRSPD GTSKGCAFVK FGSQGEAQAA IRGLHGSRTM AGASSSLVVK LADTDRERAL RRMQQMAGHL GAFHPAPLPL GACGAYTTAI LQHQAALLAA AQGPGLGPVA AVAAQMQHVA AFSLVAAPLL PAAAANSPPG SGPGTLPGLP APIGVNGFGP LTPQTNGQPG SDTLYNNGLS PYPAQSPGVA DPLQQAYAGM HHYAAAYPSA YAPVSTAFPQ QPSALPQQQR EGPEGCNLFI YHLPQEFGDA ELIQTFLPFG AVVSAKVFVD RATNQSKCFG FVSFDNPTSA QTAIQAMNGF QIGMKRLKVQ LKRPKDANRP Y
3D Structure
ModBase 3D Structure for Q96J87
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CELF6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CELF6 recombinant protein
Members of the CELF
BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation.
NCBI/Uniprot data below describe general gene information for CELF6. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001166155.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001172684.1
[Other Products]
UniProt Primary Accession #
Q96J87
[Other Products]
UniProt Secondary Accession #
Q6PII4; Q6ZNJ7; Q8N607; B4DG28; B4DJB6[Other Products]
UniProt Related Accession #
Q96J87[Other Products]
Molecular Weight
36,154 Da
NCBI Official Full Name
CUGBP Elav-like family member 6 isoform 2
NCBI Official Synonym Full Names
CUGBP Elav-like family member 6
NCBI Official Symbol
CELF6??[Similar Products]
NCBI Official Synonym Symbols
BRUNOL6
??[Similar Products]
NCBI Protein Information
CUGBP Elav-like family member 6
UniProt Protein Name
CUGBP Elav-like family member 6
UniProt Synonym Protein Names
Bruno-like protein 6; CUG-BP- and ETR-3-like factor 6; RNA-binding protein BRUNOL-6
Protein Family
CUGBP Elav-like family
UniProt Gene Name
CELF6??[Similar Products]
UniProt Synonym Gene Names
BRUNOL6; CELF-6??[Similar Products]
NCBI Summary for CELF6
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]
UniProt Comments for CELF6
RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA.
Research Articles on CELF6
1. Analysis of common variants near the corresponding genes implicated the RNA binding protein CELF6 in autism risk
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
