Product Name
Dynactin subunit 4 (Dctn4), Recombinant Protein
Full Product Name
Recombinant Mouse Dynactin subunit 4 (Dctn4)
Product Gene Name
Dctn4 recombinant protein
[Similar Products]
Product Synonym Gene Name
Dctn4[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-467aa, Full Length of Mature Protein
Sequence
ASLLQSERVL YLVQGEKKVR APLSQLYFCR YCSELRSLEC VSHEVDSHYC PSCLENMPSA EAKLKKNRCA NCFDCPGCMH TLSTRATSIS TQLPDDPAKT TMKKAYYLAC GFCRWTSRDV GMADKSVASG GWQEPENPHT QRMNKLIEYY QQLAQKEKVE RDRKKLARRR NYMPLAFSQH TIHVVDKYSL GTRLQRPRAG ASISTLAGLS LREGEDQKEV KIEPAQAVAE VEPLPEDYYT RPVNLTEVTT LQQRLLQPDL QPVSASQLYP RHKHLLIKRS LRCRKCEHNL SKPEFNPTSI KFKIQLVAVN YIPEVRIMSI PNLRYMKESQ VLLTLTNPVE NLTHVTLLEC DEGDPDNINS TAKVVVPPKE LILAGKDAAA EYDELAEPQD FQDDPDIVAF RKANKVGIFI KVTPQREEGE VTVCFKMKHD FKNLAAPIRP VEEGDQGTEV IWLTQHVELS FGPLLP
3D Structure
ModBase 3D Structure for Q8CBY8
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Dctn4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Dctn4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_080578.1
[Other Products]
NCBI GenBank Nucleotide #
NM_026302.4
[Other Products]
UniProt Primary Accession #
Q8CBY8
[Other Products]
UniProt Secondary Accession #
Q923A0; Q9D4X0[Other Products]
UniProt Related Accession #
Q8CBY8[Other Products]
Molecular Weight
52,242 Da
NCBI Official Full Name
dynactin subunit 4 isoform 1
NCBI Official Synonym Full Names
dynactin 4
NCBI Official Symbol
Dctn4??[Similar Products]
NCBI Official Synonym Symbols
p62; 1110001K06Rik; 4930547K17Rik; C130039E17Rik
??[Similar Products]
NCBI Protein Information
dynactin subunit 4
UniProt Protein Name
Dynactin subunit 4
UniProt Synonym Protein Names
Dynactin subunit p62
UniProt Gene Name
Dctn4??[Similar Products]
UniProt Comments for Dctn4
Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.
Research Articles on Dctn4
1. Ankyrin-B then interacts with dynactin-4 and dystrophin, whereas dynactin-4 collaborates with dystrophin in coordinating costamere-aligned microtubules
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
