Full Product Name
Anti-DCTN4 Mouse mAb
Product Synonym Names
OPG; TR1; OCIF; MGC29565; TNFRSF11B
Product Gene Name
anti-DCTN4 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9UJW0
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Immunogen
Purified recombinant fragment of human TNFRSF11B expressed in E Coli.
Other Notes
Small volumes of anti-DCTN4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-DCTN4 antibody
Entrez Summary: Dynactin 4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.The dynactin complex binds cargo, such as vesicles and organelles, to cytoplasmic dynein for retrograde microtubule-mediated trafficking and could feasibly be involved in the copper-regulated trafficking of ATP7B.
Applications Tested/Suitable for anti-DCTN4 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
NCBI/Uniprot data below describe general gene information for DCTN4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001129116.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001135644.1
[Other Products]
UniProt Primary Accession #
Q9UJW0
[Other Products]
UniProt Secondary Accession #
Q8TAN8; B3KWW0; D3DQH0; E5RGT5[Other Products]
UniProt Related Accession #
Q9UJW0[Other Products]
NCBI Official Full Name
dynactin subunit 4 isoform c
NCBI Official Synonym Full Names
dynactin subunit 4
NCBI Official Symbol
DCTN4??[Similar Products]
NCBI Official Synonym Symbols
P62; DYN4
??[Similar Products]
NCBI Protein Information
dynactin subunit 4
UniProt Protein Name
Dynactin subunit 4
UniProt Synonym Protein Names
Dynactin subunit p62
UniProt Gene Name
DCTN4??[Similar Products]
UniProt Synonym Gene Names
Dyn4??[Similar Products]
UniProt Comments for DCTN4
dynactin 4: Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. Belongs to the dynactin subunit 4 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Microtubule-binding; Motility/polarity/chemotaxis; Motor
Chromosomal Location of Human Ortholog: 5q33.1
Cellular Component: centrosome; cytoplasm; cytoplasmic dynein complex; cytosol; dynactin complex; nucleus
Molecular Function: protein binding; protein N-terminus binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; ER to Golgi vesicle-mediated transport; nuclear migration
Research Articles on DCTN4
1. used an extreme phenotype study to discover that variants in DCTN4, encoding a dynactin protein, are associated with time to first P. aeruginosa airway infection, chronic P. aeruginosa infection and mucoid P. aeruginosa in individuals with cystic fibrosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
