Product Name
DCTN4, Polyclonal Antibody
Popular Item
Full Product Name
DCTN4 Antibody
Product Synonym Names
Dynactin subunit 4; Dyn4; DCTN4; Dynactin subunit p62
Product Gene Name
anti-DCTN4 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9UJW0
Purity/Purification
>95%, Protein G Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Immunogen
Recombinant human Dynactin subunit 4 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-12239 / sc-12241 / sc-25730
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-DCTN4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-DCTN4 antibody
Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.
Applications Tested/Suitable for anti-DCTN4 antibody
ELISA (EIA), Western Blot (WB)
Western Blot (WB) of anti-DCTN4 antibody
Western Blot
Positive WB detected in:HepG2 whole cell lysate,Jurkat whole cell lysate,HEK293 whole cell lysate,K562 whole cell lysate,SH-SY5Y whole cell lysate,Mouse liver tissue
All lanes: DCTN4 antibody at 3.4ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 53,46,54 kDa
Observed band size: 53 kDa
NCBI/Uniprot data below describe general gene information for DCTN4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001129115.1
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NCBI GenBank Nucleotide #
NM_001135643.1
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UniProt Primary Accession #
Q9UJW0
[Other Products]
UniProt Secondary Accession #
Q8TAN8; B3KWW0; D3DQH0; E5RGT5[Other Products]
UniProt Related Accession #
Q9UJW0[Other Products]
Molecular Weight
53,152 Da
NCBI Official Full Name
dynactin subunit 4 isoform a
NCBI Official Synonym Full Names
dynactin subunit 4
NCBI Official Symbol
DCTN4??[Similar Products]
NCBI Official Synonym Symbols
P62; DYN4
??[Similar Products]
NCBI Protein Information
dynactin subunit 4
UniProt Protein Name
Dynactin subunit 4
UniProt Synonym Protein Names
Dynactin subunit p62
UniProt Gene Name
DCTN4??[Similar Products]
UniProt Synonym Gene Names
Dyn4??[Similar Products]
UniProt Entry Name
DCTN4_HUMAN
UniProt Comments for DCTN4
dynactin 4: Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. Belongs to the dynactin subunit 4 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motor; Microtubule-binding; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5q33.1
Cellular Component: centrosome; cytoplasm; cytoplasmic dynein complex; cytosol; dynactin complex; nucleus
Molecular Function: protein binding; protein N-terminus binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; cellular protein metabolic process; ER to Golgi vesicle-mediated transport; nuclear migration; post-translational protein modification; protein amino acid N-linked glycosylation via asparagine
Research Articles on DCTN4
1. used an extreme phenotype study to discover that variants in DCTN4, encoding a dynactin protein, are associated with time to first P. aeruginosa airway infection, chronic P. aeruginosa infection and mucoid P. aeruginosa in individuals with cystic fibrosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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